NCT07244042Recruiting
Effects of Modified CIMT With and Without PNF
Effects of Modified Constraint-induced Movement Therapy With and Without Proprioceptive Neuromuscular Facilitation Techniques on Upper Extremity Function in Pediatric Stroke Patients
Source: ClinicalTrials.gov · Last updated 24 Nov 2025
Brief summary (registry, in English)
This randomized clinical trial investigates the effects of modified CIMT with and without the addition of PNF techniques on upper extremity function in pediatric stroke patients, aiming to determine whether combining these approaches yields superior motor recovery.This study will be conducted as a randomized clinical trial over an intervention period of six-week. 20 pediatric stroke patients with upper extremity impairments will be randomly assigned to two groups: one receiving modified CIMT alone and the other receiving modified CIMT combined with PNF techniques. Pre- and post-intervention assessments will be conducted using standardized measures, such as Pediatric Motor Activity Log(PMAL) for upper extremity function, Modified Ashworth Scale(MAS) and Manual Ability Classification System(MACS). Muscle tone and physical activity status will also be evaluated. Data will be entered and analyzed in SPSS V-26.0 to compare improvements in motor function between the two groups, with statistical significance assessed to determine the efficacy of each intervention
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 17 Nov 2025
- Start date
- 27 Oct 2025
- Primary completion date
- 25 Jan 2026
- Lead sponsor
- Riphah International University
- Diseases
- Stroke
- NCT number
- NCT07244042
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 27 Oct 2025 to the primary completion date, 25 Jan 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with epilepsy or seizure disorder
- Patients with history of botulinum toxin injection, cognitive impairment, fracture and any surgical procedure in upper extremity
Who the study is looking for
- Paeds Patients with confirmed diagnosis of Stroke
- Children between age 5 to 13 years
- Modified Ashworth Scale spasticity level 1 and 2.
- Patients having Manual Ability Classification System Score between 3 to 6.
- GMFCS level 1 and 2
- Patient having in affected upper extremity at least 20◦ of active wrist extension starting from the full flexion, 10◦ of active extension or abduction in the thumb, and 10◦ of active extension in the metacarpophalangeal and interphalangeal joints of the other fingers
Age in the registry: 5 years to 13 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Imran Amjad Coordinator of this site? Confirm its status | Lahore | Pakistan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.