Fact CheckerSign in

NCT07245979Recruiting

Supplementation With Sirtuin Activators in Women With Increased Body Weight

Assessment of the Effect of Sirtuin Activator Supplementation on Cellular, Metabolic and Anthropometric Parameters in Women

Source: ClinicalTrials.gov · Last updated 22 May 2026

Brief summary (registry, in English)

The goal of this clinical trial is to learn if the six-month supplementation with sirtuin activators can affect metabolism in 40-to-65-year old women with increased body weight. The main questions it aims to answer are: Does sirtuin activators affect lipid and carbohydrate metabolism? Does sirtuin activators affect oxydative stress, immune functions and cell ageing? Researchers will compare sirtuin activators to a placebo (a look-alike substance that contains no drug) to see if drug sirtuin activators works to improve metabolic status. Participants will: Take sirtuin activators or a placebo every day for 6 months. Visit the university once every 3 months for checkups and tests.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
120 (estimated)
First submitted
2 Oct 2025
Start date
8 Oct 2025
Primary completion date
30 Nov 2026
Lead sponsor
Poznan University of Life Sciences
Diseases
Obesity
NCT number
NCT07245979

What you commit to

  • Study type: Interventional
  • Planned participants: 120
  • From 8 Oct 2025 to the primary completion date, 30 Nov 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • sirtuin activators administration for 3 months prior to study
  • receiving pharmacotherapy to treat obesity, diabetes or hyperlipidemia
  • post-bariatric surgery

Other illness

  • diabetes
  • cancer
  • chronic kidney, liver or autoimmune diseases

Other

  • males
  • BMI \< 25 kg/m2
  • pregnancy or breastfeeding
  • recent dieting or being on calorie restricted diet
  • alcohol addiction

Who the study is looking for

  • females
  • age: 40-65 years
  • overweight or obese: BMI \>25 kg/m2

Age in the registry: 40 years to 65 years · Sex: Female · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Poznań University of Life Sciences
Coordinator of this site? Confirm its status
PoznanPolandRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.