NCT07247877Enrolling by invitation
Research on Using Small-for-size Grafts for Auxiliary Liver Transplantation in the Treatment of Portal Hypertension
Innovative Technology Research on Using Small-for-size Grafts for Auxiliary Liver Transplantation in the Treatment of Portal Hypertension
Source: ClinicalTrials.gov · Last updated 20 May 2026
Brief summary (registry, in English)
The objective of this observational study is to compare the safety profile of auxiliary liver transplantation using small-for-size grafts with that of conventional liver transplantation and to evaluate the efficacy of this technique. The primary research question it seeks to investigate is: "What are the differences in safety and efficacy between auxiliary liver transplantation utilizing small-for-size grafts and conventional liver transplantation for the treatment of portal hypertension?"
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 396 (estimated)
- First submitted
- 18 Nov 2025
- Start date
- 1 Jan 2014
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- Zhi-Jun Zhu
- Diseases
- High blood pressure
- NCT number
- NCT07247877
What you commit to
- Study type: Observational
- Planned participants: 396
- From 1 Jan 2014 to the primary completion date, 31 Dec 2028
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Special surgical procedures such as dual-graft liver transplantation.
- Special graft sources including domino liver transplantation.
- Liver re-transplantation.
Other illness
- Presence of contraindications to liver transplantation combined with malignant tumors.
- Grade III or higher portal vein thrombosis.
- Severe systemic diseases unrelated to the etiology or complications of portal hypertension.
Other
- Rare liver-related anatomical variations.
Who the study is looking for
- Age \> 14 years.
- Presence of decompensated portal hypertension.
- Meeting the indications for liver transplantation surgery.
- International Normalized Ratio (INR) \< 2.4.
- Scheduled to undergo orthotopic auxiliary partial liver transplantation or conventional liver transplantation.
Age in the registry: 14 years to - · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.