NCT07249567Completed
Comparison of Patients With COPD and PRISM
Comparison of Respiratory and Peripheral Muscle Strength, Exercise Capacity, and Muscle Oxygenation in Individuals With COPD and PRISM
Source: ClinicalTrials.gov · Last updated 29 Oct 2026
Brief summary (registry, in English)
COPD is a preventable and treatable lung disease characterized by persistent and progressive airflow limitation. PRISm, on the other hand, is a spirometry pattern that does not meet COPD diagnostic criteria despite symptoms and functional impairments, but requires maintenance. PRISm can predispose to the development of COPD and exacerbations, and can reduce exercise capacity by reducing respiratory function and oxygen consumption. There are no studies in the literature comparing respiratory muscle strength, peripheral muscle strength, and oxygenation in PRISm, COPD, and healthy individuals. Therefore, this study aimed to evaluate these parameters and compare them with healthy individuals.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 91 (actual)
- First submitted
- 18 Nov 2025
- Start date
- 5 Oct 2025
- Primary completion date
- 5 Mar 2026
- Lead sponsor
- Karabuk University
- Diseases
- COPD
- NCT number
- NCT07249567
What you commit to
- Study type: Observational
- Participants enrolled: 91
- From 5 Oct 2025 to the primary completion date, 5 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Being on clinically unstable medication,
Other illness
- Having severe orthopedic, neurological, or cardiac diseases,
- Having a comorbid lung disease,
- Having severe orthopedic, neurological, or cardiac diseases,
- Having a comorbid lung disease,
- Having a known chronic disease,
Other
- For the COPD group:
- Being in a COPD exacerbation,
- Voluntarily not participating in the study.
- For the PRISm group:
- Being diagnosed with COPD,
- Voluntarily not participating in the study.
- For the healthy control group:
- Voluntarily not participating in the study.
Who the study is looking for
- For the COPD group:
- Being \>40 years old,
- Being diagnosed with COPD,
- Being clinically stable,
- Volunteering to participate in the study.
- For the PRISm group:
- Being \>40 years old,
- Being diagnosed with PRISm,
- Volunteering to participate in the study.
- For the healthy control group:
- Being \>40 years old,
- Volunteering to participate in the study.
Age in the registry: 40 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Karabuk University, Physiotherapy and Rehabilitation Application and Research Center Coordinator of this site? Confirm its status | Karabük | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.