NCT07249788RecruitingPhase 4
Resmiterom Efficacy & Safety in Patients With MASH
Clinical Evaluation of Safety and Efficacy of Resmiterom in Patients With MASH (Metabolic Dysfunction-Associated Steato-Hepatitis) A Prospective, Open-label, Interventional Study
Source: ClinicalTrials.gov · Last updated 3 Dec 2025
Brief summary (registry, in English)
Phase 4 clinical trial study aims to further evaluate the safety and therapeutic efficacy of Resmetirom in Pakistani patients with fibroscan proven MASH.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 165 (estimated)
- First submitted
- 18 Nov 2025
- Start date
- 17 Oct 2025
- Primary completion date
- 16 Oct 2026
- Lead sponsor
- Nabiqasim Industries (Pvt) Ltd
- Diseases
- Fatty liver disease (MASLD/MASH)
- NCT number
- NCT07249788
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 165
- From 17 Oct 2025 to the primary completion date, 16 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- • History of drug addiction and alcoholism
- Cirrhosis or decompensated liver disease
- Chronic viral hepatitis HBV, HCV)
- MACE including MI, Stroke, PE etc.
- Pregnant/lactating women
- Concurrent use of other investigational drugs
- History of other liver diseases (viral, autoimmune, drug-induced, alcohol)
- Previous use of resmetirom in last 6 months
- Significant renal impairment (eGFR \<30)
Who the study is looking for
- • At least one metabolic comorbidity (e.g., T2DM, obesity, dyslipidemia and hypertension)
- Clinical diagnosis of MASH using:
- LSM ≥ 8.5kpa And/or
- FAST score ≥0.67 And/or
- FibroScan CAP ≥ 275 dB/m And/or
- FIB-4 \> 1.3
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Liver transplant center, Holy family hospital Coordinator of this site? Confirm its status | Rawalpindi | Pakistan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.