NCT07251517Completed
Cognitive Rehabilitation in Post-stroke Cognitive Impairment
Cognitive Impairment Post Stroke: a Single-blinded Randomized Trial on the Efficacy of TEleRehabilitation. The CIPS-TER Study
Source: ClinicalTrials.gov · Last updated 29 Apr 2026
Brief summary (registry, in English)
The goal of this 2-year, prospective, single-blind randomized clinical trial is to investigate: the efficacy in reducing the risk of cognitive impairment 6 months after stroke; the generalizability of cognitive reinforcement to real life, such as activities of daily living and quality of life; and the impact on cognitive performance. In the treatment group, feasibility, adherence, and satisfaction with the cognitive telerehabilitation program will also be evaluated. Participants will be adult patients with a diagnosis of ischemic or hemorrhagic stroke, within 5-21 days after onset. The main outcomes to be evaluated are: * diagnosis of cognitive impairment (primary outcome); * activities of daily living, quality of life, changes in frailty status, and cognitive efficiency (secondary outcomes). There will be two groups: a treatment group and a control group. Participants in the treatment group will undergo a cognitive telerehabilitation program of 40 hours over 8 weeks, while participants in the control group will be instructed to follow their standard care.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 86 (actual)
- First submitted
- 2 Oct 2025
- Start date
- 22 Apr 2024
- Primary completion date
- 20 Mar 2026
- Lead sponsor
- University of Florence
- Diseases
- Stroke
- NCT number
- NCT07251517
What you commit to
- Study type: Interventional
- Participants enrolled: 86
- From 22 Apr 2024 to the primary completion date, 20 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Pre-existing dementia (IQ-CODE\>3.48 and/or diagnosis of dementia by a specialist).
Other
- Severe aphasia (NIHSS language item ≥2 and impaired performance on the Token test, i.e. a correct score below the 5th centile of the normal population).
- Withdrawal of informed consent
Who the study is looking for
- Age ≥ 18 years
- Diagnosis of ischemic or hemorrhagic stroke between 5 and 21 days after the event
- Ability to express written informed consent
- Evidence of impairment of global cognitive efficiency according to the post-stroke MoCA (MoCA total score≤21)
- Normal stenia of at least one upper limb (NIHSS motor item of at least one upper limb=0)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Florence Coordinator of this site? Confirm its status | Florence | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.