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NCT07251920CompletedPhase 3

Isometric Resistance Training and Dose-dependent Effects in Pre- and Hypertensive Adults

Examination of the Dose-dependent Effects of Isometric Resistance Training on Decreases in Blood Pressure in Pre- and Hypertensive Adults

Source: ClinicalTrials.gov · Last updated 26 Nov 2025

Brief summary (registry, in English)

High blood pressure is prevalent in a third of the global population and is a key risk factor for cardiovascular disease, the leading cause of death. one lifestyle change that is recommended to reduce blood pressure is to exercise, typically by performing aerobic exercise, but this is often not well adhered to, given the physical and time demands associated with it. Isometric resistance training has been evidenced as an efficacious method to reduce blood pressure, even when performing four two-minute contractions per day, three days per week at 30% of maximum effort. At present, the dose-response effects have not been examined, which are required to identify the minimal effective dose, which could further reduce the temporal demands of this modality to potentially enhance adhernece even more in time-anxious individuals. Therefore, this study aimed to compare the efficacy of once- twice-, and thrice-weekly isometric resistance training programmes to lower blood pressure,

Status (registry)
Completed
Phase (registry)
Phase 3
Study type
Interventional
Enrollment
30 (actual)
First submitted
18 Nov 2025
Start date
19 Feb 2024
Primary completion date
20 May 2024
Lead sponsor
The University of Northampton
NCT number
NCT07251920

What you commit to

  • Study type: Interventional · Phase 3
  • Participants enrolled: 30
  • From 19 Feb 2024 to the primary completion date, 20 May 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • currently taking anti-hypertensive medication

Other

  • conditoned to resistance training
  • regularly smoke or vape
  • are pregnant

Who the study is looking for

  • not taking anti-hypertensive medication
  • borderlerine hypertensive or hypertensive (systolic blood pressure \>139 mmHG, diastolic blood pressure \> 89 mmHg

Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University of Northampton, Waterside Campus
Coordinator of this site? Confirm its status
NorthamptonUnited KingdomUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.