EXOPULSE Suit and Walking Ability of Patients With Multiple Sclerosis

Prior treatment

• Person using an electronic life-support equipment, e.g. pacemakers or hight-frequency surgical equipment and person using an ECG equipment
• Person with relapses over the last 3 months before the inclusion
• Person who had a modification of his/her medical treatments of the multiple sclerosis or related to motor performance over the last 3 months before the inclusion
• Person who had a new medical treatment of the multiple sclerosis or related to motor performance over the last 3 months before the inclusion
• Person who had an injection of botulinum toxin in at least one of the main muscle groups of the lower limbs over the last 4 months before the inclusion

Other illness

• Person affected by other somatic or neuropsychiatric diagnoses (e.g., arrhythmias, uncontrolled epilepsy, diseases causing osteoarticular and muscular pain).

Age

• Person under 18 years old

Other

• Person having a contraindication to using EXOPULSE SUIT
• Person planning to use a new medical device during the study (ex: ankle-foot orthosis…)
• Person undergoing or planning to undergo an intensive rehabilitation phase
• Person that is part of another study
• Person who cannot be fitted with EXOPULSE SUIT due to inexistent Suitable size of the Suit (eg: BMI\>35; user height \< 100 cm or \> 205cm)
• Person who does not have a smartphone or who cannot or does not want to use his/her smartphone for operating the EXOPULSE App
• Person not available to undergo all medical visits during the study
• Person unable to understand verbal and written instructions in french
• Pregnant person
• Persons under juridical protection
• Prisoners

• Person with a clear Multiple Sclerosis diagnosis according to the 2017 revision of the McDonald criteria since at least 3 months.
• Person with an Expanded Disability Status Scale (EDSS) score ≥ 4 and ≤ 6
• Person with stable walking ability for at least two weeks prior to the inclusion visit (variation at the MSWS-12 questionnaire \< 8/100 points)
• Person not treated with fampridine due to contra-indication or adverse events or not respondent or no longer respondent or reluctant to taking drugs
• Person with spasticity at the lower limb(s), attested by a Modified Ashworth Scale ≥ 1+ of at least one of the following muscle groups: quadriceps, hamstrings, triceps surae, tibialis anterior
• Person who never tried EXOPULSE SUIT