NCT07253870Recruiting
Comperative Effects of Transcutaneous Auricular and Cervical Vagus Nerve Stimulation in Subacute Stroke Patients
Comparative Effects of Transcutaneous Auricular and Cervical Vagus Nerve Stimulation on Upper Limb Function, Cognition and Quality of Life in Subacute Stroke Patients
Source: ClinicalTrials.gov · Last updated 18 Jun 2026
Brief summary (registry, in English)
This study aims to determine whether transcutaneous vagus nerve stimulation (tVNS) via auricular or cervical branches enhances recovery when combined with task-specific training in subacute stroke patients. We anticipate finding that both stimulation methods may improve upper limb motor function compared to conventional therapy. The research is expected to reveal specific cognitive domains (attention, memory, executive function) that benefit most from each stimulation approach, while also demonstrating meaningful improvements in patients' quality of life measures. These findings may make a significant practical contribution by providing clinicians with evidence-based guidance on suitable tVNS approach for improving functional independence and quality of life for stroke survivors.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 54 (estimated)
- First submitted
- 19 Nov 2025
- Start date
- 20 Nov 2025
- Primary completion date
- 20 Jun 2026
- Lead sponsor
- Lahore University of Biological and Applied Sciences
- Diseases
- Stroke
- NCT number
- NCT07253870
What you commit to
- Study type: Interventional
- Planned participants: 54
- From 20 Nov 2025 to the primary completion date, 20 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous injury or surgical intervention of vagus nerve
Other illness
- Patients with cardiac arrest and arrythmias
- Uncontrolled hypertension
- Other neurologic or musculoskeletal diseases
Other
- Apraxia
- Presence of implanted electronic devices
Who the study is looking for
- First ever ischemic stroke
- Subacute phase of stroke 3-6 months post onset
- Fugl-Meyer Assessment-Upper Extremity (FMA-UE) scores ranged from 20 - 50
Age in the registry: 45 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shadman Medical Center, Stroke Rehabilitation Coordinator of this site? Confirm its status | Lahore | Pakistan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.