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NCT07253948Recruiting

Distribution Characteristics of Helicobacter Pylori

Distribution Characteristics of Helicobacter Pylori in Different Gastritis and Early Gastric Cancer States Using Immunohistochemical Staining

Source: ClinicalTrials.gov · Last updated 28 Nov 2025

Brief summary (registry, in English)

This study aimed to analyze the distribution characteristics of Helicobacter pylori(H. pylori) in varying stages of atrophic gastritis and early gastric cancer using immunohistochemical staining, with the goal of providing guidance for the early screening of gastric cancer. A retrospective analysis was conducted on gastric biopsy cases that underwent H. pylori immunohistochemical staining at our center from March 1, 2023, to August 15, 2025. Cases were classified into non-atrophic and atrophic groups based on the presence or absence of gastric atrophy. All cases were further divided into non-open and open atrophy groups and additionally into early gastric cancer and non-cancer groups. The distribution of H. pylori across subgroups was compared, and multivariate analyses were performed to identify risk factors associated with the development of early gastric cancer.

Status (registry)
Recruiting
Study type
Observational
Enrollment
231 (estimated)
First submitted
13 Nov 2025
Start date
22 Oct 2025
Primary completion date
31 Dec 2025
Lead sponsor
Jilin University
NCT number
NCT07253948

What you commit to

  • Study type: Observational
  • Planned participants: 231
  • From 22 Oct 2025 to the primary completion date, 31 Dec 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • history of stomach surgery
  • suspected autoimmune gastritis under endoscopy
  • severe comorbidities such as advanced cancer or renal failure
  • advanced gastric cancer or gastric lymphoma

Other

  • biopsies not collected from both the greater and lesser curvatures of the gastric antrum and body
  • liver cirrhosis

Who the study is looking for

  • age 18-80 years
  • received H. pylori immunohistochemical testing at our center and tested positive.

Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
The First Hospital of Jilin University
Coordinator of this site? Confirm its status
ChangchunChinaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.