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NCT07257562Recruiting

Combined Use of Bacteroides Fragilis and BCAAs on HBsAg Clearance

A Prospective Observational Study on the Effects of Concomitant Administration of Bacteroides Fragilis and Branched-Chain Amino Acids on HBsAg Clearance

Source: ClinicalTrials.gov · Last updated 2 Dec 2025

Brief summary (registry, in English)

The goal of this prospective observational study is to determine the effects of concomitant administration of Bacteroides fragilis and Branched-Chain Amino Acids on hepatitis B virus clearance. The primary question it aims to answer is whether this concomitant administration can promote HBV clearance. The study will observe the HBV clearance rate in chronic hepatitis B patients who receive Bacteroides fragilis and BCAA as a supplement to their routine antiviral therapy. For comparison, researchers will compare the clearance rate in this group to that observed in a control group of chronic hepatitis B patients receiving a standard antiviral regimen based on PegIFNα2b and nucleoside analogs.

Status (registry)
Recruiting
Study type
Observational
Enrollment
40 (estimated)
First submitted
17 Nov 2025
Start date
1 Jun 2025
Primary completion date
1 Mar 2026
Lead sponsor
First Affiliated Hospital of Fujian Medical University
Diseases
Hepatitis B
NCT number
NCT07257562

What you commit to

  • Study type: Observational
  • Planned participants: 40
  • From 1 Jun 2025 to the primary completion date, 1 Mar 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • patients with malignancies
  • patients with other liver diseases

Other

  • pregnancy patients

Who the study is looking for

  • \- chronic hepatitis B patients

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
The First Affiliated Hospital of Fujian Medical University
Coordinator of this site? Confirm its status
FuzhouChinaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.