NCT07258186Recruiting
Generation of Endometrial Carcinoma Organoids
Feasibility Study of the Generation of Endometrial Carcinoma Organoids From Tumor Samples Transferred From Extramural Facilities
Source: ClinicalTrials.gov · Last updated 2 Dec 2025
Brief summary (registry, in English)
A prospective pilot genetic study to evaluate the feasibility of generating organoids from endometrial tumor tissue collected during surgery, performed according to standard clinical practice. Samples will be collected from collaborating extramural facilities, with the aim of analyzing the impact of transport on tissue viability and the success of organoid culture. This study is for exploratory purposes only, without altering the diagnostic and therapeutic pathways of the participants.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 20 (estimated)
- First submitted
- 18 Nov 2025
- Start date
- 23 Mar 2025
- Primary completion date
- 23 Sept 2028
- Lead sponsor
- Regina Elena Cancer Institute
- Diseases
- Endometrial cancer
- NCT number
- NCT07258186
What you commit to
- Study type: Observational
- Planned participants: 20
- From 23 Mar 2025 to the primary completion date, 23 Sept 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Comorbidities not controlled with adequate medical therapy;
- Previous radiation treatments to the pelvic region.
Other illness
- Endometrial cavity infections (pyometra);
Other
- Synchronous tumors;
- Neoadjuvant treatments;
Who the study is looking for
- Age \>18 years;
- Patients with a histological diagnosis of: endometrial cancer, endometrioid histology, any stage of disease (FIGO I-IV), recurrence/metastasis from endometrial endometrioid cancer, and candidates for surgery and/or hysterectomy;
- Written informed consent (study participation and data processing) must be obtained in person and/or through a legal representative/guardian/support administrator/witness, before any study-specific procedure is performed.
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| IRCCS National Cancer Institute "Regina Elena" Coordinator of this site? Confirm its status | Roma | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.