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NCT07258251Not yet recruitingPhase 4

Strengthening Hepatitis B Screening, Linkage to Care and Long-Term Monitoring in Phichit Province, Thailand: A Birth Bohort Approach

Source: ClinicalTrials.gov · Last updated 2 Dec 2025

Brief summary (registry, in English)

This study in Phichit province, Thailand, aims to find and support adults born before 1992 who are at high risk for hepatitis B infection. Many people in this group were born before the universal hepatitis B vaccine was available and may not know they are infected. The study will invite nearly 240,000 eligible adults for free hepatitis B screening. Those who test positive will be linked to care at one of 12 district hospitals. Doctors will use simplified 2024 World Health Organization (WHO) guidelines to decide who needs treatment. Eligible individuals will receive a safe, effective daily medicine (tenofovir alafenamide). The study will use community health volunteers and phone reminders to help patients stay in care and take their medication regularly. Over three years, the study will track improvements in liver health and virus levels, aiming to prevent liver cirrhosis and cancer.

Status (registry)
Not yet recruiting
Phase (registry)
Phase 4
Study type
Interventional
Enrollment
6000 (estimated)
First submitted
20 Nov 2025
Start date
1 Jan 2026
Primary completion date
31 Dec 2028
Lead sponsor
The Task Force for Global Health
Diseases
Hepatitis B
NCT number
NCT07258251

What you commit to

  • Study type: Interventional · Phase 4
  • Planned participants: 6000
  • From 1 Jan 2026 to the primary completion date, 31 Dec 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Subjects who withdraw consent

Who the study is looking for

  • Adults born before January 1, 1992
  • Residing in Phichit Province
  • Individuals who test positive for HBsAg will be invited to participate in the follow-up cohort
  • HBsAg positive patients who are already under care will also be invited to participate

Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Phichit Provincial Hospital, Phichit / 12 District Hospitals in Phichit Province
Coordinator of this site? Confirm its status
PhichitThailandUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.