NCT07259772Active, not recruitingPhase 4
Anesthetic Effect of Ropivacaine on Local Infiltration Anesthesia in Arteriovenous Fistula Surgery
Anesthetic Effect of Ropivacaine on Local Infiltration Anesthesia in Arteriovenous Fistula Surgery: a Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 9 Dec 2025
Brief summary (registry, in English)
This study compares two local anesthetics, ropivacaine and lidocaine, for patients undergoing arteriovenous fistula surgery. Arteriovenous fistula is the preferred vascular access for end-stage kidney disease patients needing hemodialysis. In this clinical trial, patients are randomly assigned to receive either ropivacaine or lidocaine for local anesthesia during the surgery. Researchers are evaluating which medication provides better pain control and improves surgical outcomes. The study is examining: * Pain levels during and after surgery * Surgery duration * Need for additional pain medication * Surgical complications * Fistula development over time * Long-term fistula function at 1 year and 5 years This is a double-blind study, meaning neither patients nor surgeons know which medication is being used. The study is currently ongoing with active patient follow-up and is expected to be completed in June 2026. Patients are being followed for up to 5 years to monitor their long-term progress. This research may help doctors choose the best local anesthetic for arteriovenous fistula surgery, potentially leading to better pain control and improved long-term outcomes for kidney disease patients.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 40 (actual)
- First submitted
- 21 Nov 2025
- Start date
- 10 Apr 2019
- Primary completion date
- 31 Mar 2021
- Lead sponsor
- The First People's Hospital of Lianyungang
- Diseases
- Chronic kidney disease
- NCT number
- NCT07259772
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 40
- From 10 Apr 2019 to the primary completion date, 31 Mar 2021
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of arteriovenous fistula on the ipsilateral limb
- Known allergy to local anesthetics (ropivacaine or lidocaine)
- Coagulopathy or bleeding disorders
- Local infection at the planned anesthesia or surgical site
- Severe peripheral neuropathy or neurological disorders affecting upper limb function
- Significant thrombosis or severe stenosis in the proximal major veins or central veins of the limb
Other
- Impaired communication abilities or inability to complete questionnaires due to language barriers, or missing essential data
- Preoperative ultrasound findings of:
- Radial or brachial artery diameter \<1.8 mm
- Cephalic vein diameter \<2 mm at the wrist or \<3 mm at the elbow (without tourniquet application)
- Pregnancy or breastfeeding
- Participation in another clinical trial within 30 days
Who the study is looking for
- Adult patients (aged ≥18 years) scheduled for primary radiocephalic arteriovenous fistula creation
- Diagnosed with end-stage renal disease requiring hemodialysis
- Willing and able to provide written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Lianyungang First People's Hospital Coordinator of this site? Confirm its status | Lianyungang | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.