NCT07261579Completed
Composite Ratios Boost CRP's Power in Monitoring Ulcerative Colitis.
Composite Inflammatory Parameters Ratios Enforce the Role of CRP for Monitoring Ulcerative Colitis Disease Activity
Source: ClinicalTrials.gov · Last updated 21 Jan 2026
Brief summary (registry, in English)
Inflammatory Bowel Disease (IBD) is a chronic, recurrent condition marked by disturbed levels of various hematological inflammatory cells and a deregulated immune environment. While C-reactive protein (CRP) is a key acute-phase reactant, its high levels can persist even after inflammation subsides. Other simple, cost-effective ratios, such as the Neutrophil-to-Lymphocyte Ratio (NLR), the Platelet-to-Lymphocyte Ratio (PLR), and Albumin-related ratios, also serve as promising, reproducible markers of systemic inflammation reflecting both immune status and nutrition. This study's objective is to evaluate the diagnostic performance of these various hematological inflammatory cellular components and CRP-related ratios (like the CAR) as predictors for Ulcerative Colitis (UC) disease severity, using colonoscopic and microscopic findings as the gold standard for comparison.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 80 (actual)
- First submitted
- 22 Nov 2025
- Start date
- 15 Sept 2025
- Primary completion date
- 25 Nov 2025
- Lead sponsor
- Benha University
- Diseases
- Ulcerative colitis
- NCT number
- NCT07261579
What you commit to
- Study type: Observational
- Participants enrolled: 80
- From 15 Sept 2025 to the primary completion date, 25 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who was Previously diagnosed with IBD or IBS;
- Patients with recurrence of manifestations after surgical resection;
Other
- Patients who refused to sign the participation consent.
Who the study is looking for
- Patients who fulfilled the diagnostic criteria for UC;
- Patients were free of exclusion criteria;
- Patients who signed the written consent were enrolled in the study
Age in the registry: 18 years to 45 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Alexandria Faculty of medicine Coordinator of this site? Confirm its status | Alexandria | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.