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NCT07261579Completed

Composite Ratios Boost CRP's Power in Monitoring Ulcerative Colitis.

Composite Inflammatory Parameters Ratios Enforce the Role of CRP for Monitoring Ulcerative Colitis Disease Activity

Source: ClinicalTrials.gov · Last updated 21 Jan 2026

Brief summary (registry, in English)

Inflammatory Bowel Disease (IBD) is a chronic, recurrent condition marked by disturbed levels of various hematological inflammatory cells and a deregulated immune environment. While C-reactive protein (CRP) is a key acute-phase reactant, its high levels can persist even after inflammation subsides. Other simple, cost-effective ratios, such as the Neutrophil-to-Lymphocyte Ratio (NLR), the Platelet-to-Lymphocyte Ratio (PLR), and Albumin-related ratios, also serve as promising, reproducible markers of systemic inflammation reflecting both immune status and nutrition. This study's objective is to evaluate the diagnostic performance of these various hematological inflammatory cellular components and CRP-related ratios (like the CAR) as predictors for Ulcerative Colitis (UC) disease severity, using colonoscopic and microscopic findings as the gold standard for comparison.

Status (registry)
Completed
Study type
Observational
Enrollment
80 (actual)
First submitted
22 Nov 2025
Start date
15 Sept 2025
Primary completion date
25 Nov 2025
Lead sponsor
Benha University
NCT number
NCT07261579

What you commit to

  • Study type: Observational
  • Participants enrolled: 80
  • From 15 Sept 2025 to the primary completion date, 25 Nov 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients who was Previously diagnosed with IBD or IBS;
  • Patients with recurrence of manifestations after surgical resection;

Other

  • Patients who refused to sign the participation consent.

Who the study is looking for

  • Patients who fulfilled the diagnostic criteria for UC;
  • Patients were free of exclusion criteria;
  • Patients who signed the written consent were enrolled in the study

Age in the registry: 18 years to 45 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Alexandria Faculty of medicine
Coordinator of this site? Confirm its status
AlexandriaEgyptUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.