NCT07263282Not yet recruiting
LA Strain in Predicting Early Complication in STEMI After PPCI
Left Atrium Strain as a Predictor of In-Hospital Outcomes in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention
Source: ClinicalTrials.gov · Last updated 12 Dec 2025
Brief summary (registry, in English)
The goal of this observational study To evaluate the predictive value of left atrial strain for in-hospital outcomes in patients with ST-segment elevation myocardial infarction undergoing PPCI. The main questions it aims to answer are: Is low parameters of left atrial strain associated early complication ? What is the correlation between LA strain parameters and conventional echocardiographic indices of left ventricular systolic and diastolic function ? Is there more affection to LA strain in certain territory over the others ? What is the correlation between LA strain and LA volume index across infarct territories ? Does LA strain Correlate with TAPSE and PASP to evaluate right-heart interactions ?
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 135 (estimated)
- First submitted
- 16 Nov 2025
- Start date
- 1 Dec 2025
- Primary completion date
- 1 Dec 2026
- Lead sponsor
- Assiut University
- Diseases
- Coronary artery disease
- NCT number
- NCT07263282
What you commit to
- Study type: Observational
- Planned participants: 135
- From 1 Dec 2025 to the primary completion date, 1 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous myocardial infarction or prior PCI/CABG.
- Prior cardiac surgery or known structural lesions that preventing reliable LA measurement.
Other illness
- Patients known to have atrial fibrillation or other sustained supraventricular arrhythmias.
- Significant valvular heart disease (severe stenosis or regurgitation).
- Congenital heart disease or cardiomyopathy (hypertrophic, dilated, restrictive).
Other
- Poor echocardiographic window preventing LA strain analysis .
- Mechanical complications (e.g., papillary muscle rupture, VSD, free wall rupture).
- patient presenting with killip class III or IV from the start
Who the study is looking for
- Adults aged ≥18 years.
- Diagnosed with ST-segment elevation myocardial infarction (STEMI) according to current ESC/AHA criteria
- Underwent successful primary percutaneous coronary intervention (PPCI) within 12 hours of symptom onset.
- Sinus rhythm on admission .
- Trans thoracic echocardiography (TTE) performed within 48 hours of admission with adequate image quality for speckle-tracking analysis.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Assiut University Coordinator of this site? Confirm its status | Asyut | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.