NCT07267780Not yet recruiting
Contribution of Oncovascular Surgery in the Treatment of Gynecological Advanced Malignant Diseases.
The Contribution of Oncovascular Surgery in the Treatment of Gynecological Advanced Malignant Diseases: a Prospective and Retrospective Multicenter Study
Source: ClinicalTrials.gov · Last updated 5 Dec 2025
Brief summary (registry, in English)
Multicenter ambispective observational study (prospective/retrospective)
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 130 (estimated)
- First submitted
- 22 Sept 2025
- Start date
- Dec 2025
- Primary completion date
- Dec 2030
- Lead sponsor
- National Cancer Institute, Naples
- Diseases
- Endometrial cancer, Cervical cancer, Ovarian cancer, Sarcoma
- NCT number
- NCT07267780
What you commit to
- Study type: Observational
- Planned participants: 130
- From Dec 2025 to the primary completion date, Dec 2030
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients undergoing vascular resection due to accidental injury of blood vessels not directly related to tumor infiltration.
- Patients who have previously undergone vascular surgery for reasons unrelated to the study, to avoid data overlap.
Other illness
- Patients with early-stage gynecologic cancers not eligible for onco-vascular surgery
Age
- Patients younger than 18 years of age
Who the study is looking for
- \- Retrospective Arm:
- Diagnosis of advanced or recurrent gynecologic cancer with vascular involvement requiring resection and/or reconstruction of major blood vessels, including:
- Ovarian carcinoma
- Cervical carcinoma
- Endometrial carcinoma
- Vulvar carcinoma
- Uterine or other types of sarcomas with vascular involvement
- Documented major vascular invasion, confirmed by preoperative imaging or intraoperative description.
- Patients who underwent onco-vascular surgery for advanced or recurrent gynecologic cancers between January 1, 2017, and August 31, 2025.
- Data Protection Impact Assessment (DPIA) approved for the management of retrospective data. (Deceased or untraceable patients will also be included to avoid selection bias, in accordance with Article 110 bis, paragraph 4 of the Italian Privacy Code. A DPIA will be produced and published on the Sponsor's website before study initiation, and patients who explicitly objected before death will not be included.)
- Prospective Arm:
- Age ≥18 years
- Patients eligible for onco-vascular surgery for advanced or recurrent gynecologic cancers with vascular involvement, including:
- Ovarian carcinoma
- Cervical carcinoma
- Endometrial carcinoma
- Vulvar carcinoma
- Uterine or other types of sarcomas
- Documented major vascular invasion, confirmed by preoperative imaging or intraoperative description.
- Signed informed consent.
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" Coordinator of this site? Confirm its status | Naples | Italy | Unknown status |
| A.R.N.A.S. Ospedali Civico Di Cristina Benfratell Coordinator of this site? Confirm its status | Palermo | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.