NCT07269366Recruiting
Surgical Versus Percutaneous Revascularization in Patients With Reduced Left Ventricular Function (STICH 3.0-NL)
Surgical Versus Percutaneous Revascularization in Patients With Reduced Left Ventricular Function
Source: ClinicalTrials.gov · Last updated 12 May 2026
Brief summary (registry, in English)
This randomized multicenter trial compares coronary artery bypass grafting (CABG) with percutaneous coronary intervention (PCI) in 358 patients with ischemic left ventricular dysfunction and multivessel coronary disease. The study evaluates differences in survival, major cardiovascular events, and quality of life over 4 years, and contributes to the international STICH 3.0 collaboration assessing long-term outcomes.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 358 (estimated)
- First submitted
- 20 Nov 2025
- Start date
- 1 May 2026
- Primary completion date
- 31 May 2034
- Lead sponsor
- University Medical Center Groningen
- Diseases
- Heart failure, Coronary artery disease
- NCT number
- NCT07269366
What you commit to
- Study type: Interventional
- Planned participants: 358
- From 1 May 2026 to the primary completion date, 31 May 2034
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous CABG
Other illness
- Valvular/structural heart disease requiring intervention
- Non-cardiac condition with life expectancy \< 1 year
Other
- ACS \< 48 hours before randomization
- Contra-indications to DAPT
- Decompensated HF at the time of inclusion
Who the study is looking for
- Age ≥ 18 years
- LVEF≤ 40%
- Angina pectoris, CCS≥2 and/or hospitalization for ACS or heart failure within 1 year prior to randomization
- Multivessel CAD (2-3 vessel-disease with coronary lesions \>70% and involvement of proximal LAD, and/or LM stenosis of \>50%). Target vessels are determined by the local Heart Time
- Clinical and angiographical characteristics suitable for isolated coronary revascularization both by CABG or PCI according to the judgment of the local Heart Team
- Written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Medical Center Groningen Coordinator of this site? Confirm its status | Groningen | Netherlands | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.