NCT07271914Not yet recruiting
PONDER: Pelvic Peritonectomy in Early Stage Ovarian Tumors
Pelvic peritOnectomy iN Early Stage Ovarian Tumors: a prospEctive Study
Source: ClinicalTrials.gov · Last updated 9 Dec 2025
Brief summary (registry, in English)
Early-stage ovarian tumors represent approximately 30% of all newly diagnosed ovarian cancers. Current international guidelines recommend random peritoneal biopsies for surgical staging, but the diagnostic yield of these biopsies remains limited. The PONDER study aims to evaluate whether standardized surgical procedure and pathology assessment of wider peritoneal pelvic biopsies can increase the detection rate of microscopic peritoneal implants and micrometastases in patients with early-stage ovarian tumors. This multicenter, prospective, single-arm study includes both minimally invasive and open surgical approaches, with a standardized gross and microscopic evaluation of the resected peritoneal specimens
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 390 (estimated)
- First submitted
- 18 Nov 2025
- Start date
- Feb 2026
- Primary completion date
- Feb 2030
- Lead sponsor
- Ospedale Santa Croce-Carle Cuneo
- Diseases
- Ovarian cancer
- NCT number
- NCT07271914
What you commit to
- Study type: Interventional
- Planned participants: 390
- From Feb 2026 to the primary completion date, Feb 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Fertility-sparing surgery with uterine preservation
Other illness
- Sarcomas, melanomas, mesotheliomas, hematologic malignancies
Other
- Advanced ovarian tumors
- Inability to provide informed consent
Who the study is looking for
- Age ≥ 18 years
- FIGO 2018 stage IA-IB epithelial or non-epithelial ovarian or fallopian tube tumors
- Complete preoperative work-up (ultrasound, CT scan, tumor markers)
- Laparoscopic, robotic or open surgical approach
- Signed informed consent
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Azienda Ospedaliera Santa Croce e Carle Cuneo Coordinator of this site? Confirm its status | Cuneo | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.