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NCT07271914Not yet recruiting

PONDER: Pelvic Peritonectomy in Early Stage Ovarian Tumors

Pelvic peritOnectomy iN Early Stage Ovarian Tumors: a prospEctive Study

Source: ClinicalTrials.gov · Last updated 9 Dec 2025

Brief summary (registry, in English)

Early-stage ovarian tumors represent approximately 30% of all newly diagnosed ovarian cancers. Current international guidelines recommend random peritoneal biopsies for surgical staging, but the diagnostic yield of these biopsies remains limited. The PONDER study aims to evaluate whether standardized surgical procedure and pathology assessment of wider peritoneal pelvic biopsies can increase the detection rate of microscopic peritoneal implants and micrometastases in patients with early-stage ovarian tumors. This multicenter, prospective, single-arm study includes both minimally invasive and open surgical approaches, with a standardized gross and microscopic evaluation of the resected peritoneal specimens

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
390 (estimated)
First submitted
18 Nov 2025
Start date
Feb 2026
Primary completion date
Feb 2030
Lead sponsor
Ospedale Santa Croce-Carle Cuneo
NCT number
NCT07271914

What you commit to

  • Study type: Interventional
  • Planned participants: 390
  • From Feb 2026 to the primary completion date, Feb 2030
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Fertility-sparing surgery with uterine preservation

Other illness

  • Sarcomas, melanomas, mesotheliomas, hematologic malignancies

Other

  • Advanced ovarian tumors
  • Inability to provide informed consent

Who the study is looking for

  • Age ≥ 18 years
  • FIGO 2018 stage IA-IB epithelial or non-epithelial ovarian or fallopian tube tumors
  • Complete preoperative work-up (ultrasound, CT scan, tumor markers)
  • Laparoscopic, robotic or open surgical approach
  • Signed informed consent

Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Azienda Ospedaliera Santa Croce e Carle Cuneo
Coordinator of this site? Confirm its status
CuneoItalyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.