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NCT07273201Recruiting

Isolated Versus Synergetic Muscle Facilitation on Upper Limb Functional Performance in Acute Stroke

Effect of Isolated Versus Synergetic Muscle Facilitation on Upper Limb Functional Performance in Patients With Acute Stroke

Source: ClinicalTrials.gov · Last updated 9 Dec 2025

Brief summary (registry, in English)

This study is a randomized controlled clinical trial that will be carried out to investigate the effect of isolated versus synergetic muscle facilitation on upper limb functional performance in patients with acute stroke. RESEARCH QUESTION: Is there a difference between isolated and synergetic muscle facilitation on upper limb functional performance in patients with acute stroke? It will be hypothesized that: There will be no difference between isolated and synergetic muscle facilitation on upper limb task-oriented training in patients with acute stroke. Treatment procedures: Study group (A): patients will receive a physical therapy program in the form of a range of motion exercise, electrical muscle stimulation, stretching exercise, mental practice with motor imagery, and isolated muscle facilitation using electromyography (EMG) biofeedback for six weeks and followed by task-oriented training of the upper limb for six weeks control group (B): will receive a standard physical therapy program including range of motion exercise, electrical muscle stimulation, Mental practice with motor imagery and stretching exercise, synergetic muscle facilitation for six weeks, and followed by task-oriented training of the upper limb for six weeks.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
40 (estimated)
First submitted
15 Nov 2025
Start date
1 Oct 2025
Primary completion date
30 Apr 2026
Lead sponsor
Cairo University
Diseases
Stroke
NCT number
NCT07273201

What you commit to

  • Study type: Interventional
  • Planned participants: 40
  • From 1 Oct 2025 to the primary completion date, 30 Apr 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Recurrent stroke

Other

  • Perceptual, apraxia, major cognitive deficits
  • Subjects with cerebellar lesions, painful or subluxated shoulder, any contracture or deformity of the upper extremity

Who the study is looking for

  • Unilateral Middle cerebral artery (MCA) stroke patients
  • Brunnstrom stage of recovery 1\& 2
  • Normal body mass index (18.5 - 24.99 kg/m2)
  • Dominant handedness

Age in the registry: 50 years to 60 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
faculty of Physical Therapy, Cairo University, and El kasr El-Einy hospitals
Coordinator of this site? Confirm its status
CairoEgyptRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.