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NCT07273500Completed

Precision Exercise in Obese Children With Bronchial Asthma

Precision Exercise Prescription for Obese Children With Bronchial Asthma: a Dose-dependent Study on Adiposity Biomarkers, Body Composition, and Respiratory Efficiency

Source: ClinicalTrials.gov · Last updated 24 Dec 2025

Brief summary (registry, in English)

This investigation recruited 72 pediatric patients with a confirmed bronchial asthma diagnosis. Participants were randomized into three cohorts: a control group undertaking under 75 minutes of weekly aerobic activity, a low-dose group completing 150 minutes/week, and a high-dose group performing 300 minutes/week. Exercise intensity was maintained between 50-70% of the age- adjusted maximum heart rate across 3-4 supervised sessions per week for a 12-week intervention period. Pre- and post-intervention analyses included measurements of adipose-tissue- derived adipokines, circulating inflammatory markers, body composition, and pulmonary function parameters.

Status (registry)
Completed
Study type
Interventional
Enrollment
72 (actual)
First submitted
27 Nov 2025
Start date
17 Sept 2023
Primary completion date
5 Sept 2024
Lead sponsor
Cairo University
Diseases
Obesity, Asthma
NCT number
NCT07273500

What you commit to

  • Study type: Interventional
  • Participants enrolled: 72
  • From 17 Sept 2023 to the primary completion date, 5 Sept 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Cardiovascular or musculoskeletal conditions expected to hinder the training.

Other

  • Exacerbated asthma symptoms
  • Chronic lung comorbidities

Who the study is looking for

  • Age of 8-18 years
  • Body mass index ranging from 30 to 35 kg/m2
  • Verified asthma diagnosis per the Global Initiative for Asthma (GINA) criteria
  • Moderate Onset
  • Clinically Stable
  • Maintained medication dosages in the past three months
  • Free of lower limb or spinal deformities
  • Not engaging in regular exercise regimens in the past six months.

Age in the registry: 8 years to 18 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Ragab K. Elnaggar
Coordinator of this site? Confirm its status
Al KharjSaudi ArabiaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.