NCT07273851Completed
Comparison of Propofol and Ketofol as Induction Agents for Electroconvulsive Therapy
A Randomized Controlled Trial Comparing Propofol and Ketofol for Hemodynamic Stability During Electroconvulsive Therapy
Source: ClinicalTrials.gov · Last updated 12 Dec 2025
Brief summary (registry, in English)
This randomized controlled trial will compare two anesthetic agents, propofol and ketofol (a combination of propofol and ketamine), in patients undergoing electroconvulsive therapy (ECT). Propofol is commonly used but may lower blood pressure, while ketofol may help maintain more stable cardiovascular function. The study will evaluate changes in systolic blood pressure following ECT when either propofol or ketofol is used for anesthesia induction. A total of 80 adult patients will be enrolled and randomly assigned to one of the two treatment groups. Findings may guide anesthesiologists in selecting the safest and most effective induction agent for ECT.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 80 (actual)
- First submitted
- 18 Nov 2025
- Start date
- 1 Jul 2025
- Primary completion date
- 10 Dec 2025
- Lead sponsor
- Fauji Foundation Hospital
- Diseases
- Depression
- NCT number
- NCT07273851
What you commit to
- Study type: Interventional
- Participants enrolled: 80
- From 1 Jul 2025 to the primary completion date, 10 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of chronic opioid therapy
- Pregnancy
- Known allergy or hypersensitivity to propofol or ketamine
- History of cardiovascular disease
- History of renal disease
Who the study is looking for
- Adults aged 18-65 years
- Both genders
- ASA physical status I-II
- Scheduled for electroconvulsive therapy
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Anesthesia, Fauji Foundation Hospital, Rawalpindi, Pakistan Coordinator of this site? Confirm its status | Rawalpindi | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.