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NCT07273851Completed

Comparison of Propofol and Ketofol as Induction Agents for Electroconvulsive Therapy

A Randomized Controlled Trial Comparing Propofol and Ketofol for Hemodynamic Stability During Electroconvulsive Therapy

Source: ClinicalTrials.gov · Last updated 12 Dec 2025

Brief summary (registry, in English)

This randomized controlled trial will compare two anesthetic agents, propofol and ketofol (a combination of propofol and ketamine), in patients undergoing electroconvulsive therapy (ECT). Propofol is commonly used but may lower blood pressure, while ketofol may help maintain more stable cardiovascular function. The study will evaluate changes in systolic blood pressure following ECT when either propofol or ketofol is used for anesthesia induction. A total of 80 adult patients will be enrolled and randomly assigned to one of the two treatment groups. Findings may guide anesthesiologists in selecting the safest and most effective induction agent for ECT.

Status (registry)
Completed
Study type
Interventional
Enrollment
80 (actual)
First submitted
18 Nov 2025
Start date
1 Jul 2025
Primary completion date
10 Dec 2025
Lead sponsor
Fauji Foundation Hospital
Diseases
Depression
NCT number
NCT07273851

What you commit to

  • Study type: Interventional
  • Participants enrolled: 80
  • From 1 Jul 2025 to the primary completion date, 10 Dec 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • History of chronic opioid therapy
    • Pregnancy
    • Known allergy or hypersensitivity to propofol or ketamine
    • History of cardiovascular disease
    • History of renal disease

Who the study is looking for

  • Adults aged 18-65 years
    • Both genders
    • ASA physical status I-II
    • Scheduled for electroconvulsive therapy

Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Department of Anesthesia, Fauji Foundation Hospital, Rawalpindi, Pakistan
Coordinator of this site? Confirm its status
RawalpindiPakistanUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.