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NCT07274631Recruiting

A Cohort for Inflammatory Respiratory Diseases: From Phenotyping to Personalised Medicine

Source: ClinicalTrials.gov · Last updated 20 Feb 2026

Brief summary (registry, in English)

Chronic inflammatory pulmonary diseases, including asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, cystic fibrosis (CF), primary ciliary dyskinesia (PCD) and interstitial lung diseases (ILD) are characterised by lung inflammation and remodelling. Clinical, functional, microbiological, biological, pathological and prognostic features are highly variable and heterogeneous. Several phenotypes have been described within the same pathology, as similar phenotypic traits between different pathologies, or the coexistence of components of several diagnoses in the same patient, suggesting shared underlying mechanisms that could represent new therapeutic targets, beyond the initial medical diagnosis. The objectives of this prospective study are to analyze the phenotypic characteristics (clinical, demographic, biological, morphological, pathological, and microbiological characteristics) together with respiratory exposures and underlying mechanisms involving airway epithelium and inflammation processes in a cohort of patients diagnosed with asthma, COPD, bronchiectasis, CF, PCD and ILD.

Status (registry)
Recruiting
Study type
Observational
Enrollment
470 (estimated)
First submitted
10 Jun 2025
Start date
15 Sept 2025
Primary completion date
15 Sept 2030
Lead sponsor
CHU de Reims
NCT number
NCT07274631

What you commit to

  • Study type: Observational
  • Planned participants: 470
  • From 15 Sept 2025 to the primary completion date, 15 Sept 2030
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Any condition preventing informed consent or participation

Other

  • Subjects protected by law (e.g., legal incapacity)

Who the study is looking for

  • Age ≥ 18 years
  • Follow-up for one of the following conditions: asthma, COPD, bronchiectasis (DDB), cystic fibrosis (CF), primary ciliary dyskinesia (PCD), or interstitial lung diseases (ILD)
  • Healthy volunteers (controls)

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
CHU Reims
Coordinator of this site? Confirm its status
ReimsFranceRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.