NCT07274631Recruiting
A Cohort for Inflammatory Respiratory Diseases: From Phenotyping to Personalised Medicine
Source: ClinicalTrials.gov · Last updated 20 Feb 2026
Brief summary (registry, in English)
Chronic inflammatory pulmonary diseases, including asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, cystic fibrosis (CF), primary ciliary dyskinesia (PCD) and interstitial lung diseases (ILD) are characterised by lung inflammation and remodelling. Clinical, functional, microbiological, biological, pathological and prognostic features are highly variable and heterogeneous. Several phenotypes have been described within the same pathology, as similar phenotypic traits between different pathologies, or the coexistence of components of several diagnoses in the same patient, suggesting shared underlying mechanisms that could represent new therapeutic targets, beyond the initial medical diagnosis. The objectives of this prospective study are to analyze the phenotypic characteristics (clinical, demographic, biological, morphological, pathological, and microbiological characteristics) together with respiratory exposures and underlying mechanisms involving airway epithelium and inflammation processes in a cohort of patients diagnosed with asthma, COPD, bronchiectasis, CF, PCD and ILD.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 470 (estimated)
- First submitted
- 10 Jun 2025
- Start date
- 15 Sept 2025
- Primary completion date
- 15 Sept 2030
- Lead sponsor
- CHU de Reims
- Diseases
- Cystic fibrosis, Asthma, COPD
- NCT number
- NCT07274631
What you commit to
- Study type: Observational
- Planned participants: 470
- From 15 Sept 2025 to the primary completion date, 15 Sept 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any condition preventing informed consent or participation
Other
- Subjects protected by law (e.g., legal incapacity)
Who the study is looking for
- Age ≥ 18 years
- Follow-up for one of the following conditions: asthma, COPD, bronchiectasis (DDB), cystic fibrosis (CF), primary ciliary dyskinesia (PCD), or interstitial lung diseases (ILD)
- Healthy volunteers (controls)
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU Reims Coordinator of this site? Confirm its status | Reims | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.