NCT07274670Completed
Superficial Cervical Plexus Block With Dexmedetomidine Versus Without Adjuvant in Thyroid Surgery
A Randomized Double-Blind Controlled Trial on the Effectiveness of Superficial Cervical Plexus Block With Dexmedetomidine Compared to Without Adjuvant in Thyroid Surgery
Source: ClinicalTrials.gov · Last updated 10 Dec 2025
Brief summary (registry, in English)
Efficacy of Superficial Cervical Plexus Block (SCPB) with Dexmedetomidine Adjuvant Compared to Without Adjuvant in Thyroid Surgery. This is a double-blinded, randomized controlled trial designed to evaluate the effectiveness of adding perineural dexmedetomidine to a Superficial Cervical Plexus Block (SCPB) for pain management in patients undergoing thyroid surgery. The study aims to prove that SCPB with dexmedetomidine adjuvant provides superior post-operative analgesia, lowers total opioid consumption, prolongs the time until the first analgesic request, and reduces the incidence of chronic pain three months post-surgery compared to SCPB without the adjuvant. The study will also evaluate the anti-inflammatory effect by measuring the reduction in Interleukin-6 (IL-6) levels post-operatively and compare the incidence of bradycardia as a side effect. The total required sample size is 58 subjects.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 58 (actual)
- First submitted
- 26 Nov 2025
- Start date
- 1 Jul 2025
- Primary completion date
- 30 Oct 2025
- Lead sponsor
- Udayana University
- Diseases
- Thyroid cancer
- NCT number
- NCT07274670
What you commit to
- Study type: Interventional
- Participants enrolled: 58
- From 1 Jul 2025 to the primary completion date, 30 Oct 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with a history of autoimmune disease.
- Presence of infection in the puncture area.
- Patients with allergies and contraindications to the use of dexmedetomidine.
- Patients on routine medication, including beta-blockers, anti-depressants, or anti-seizure medications.
Other
- Patients with contraindications for regional anesthesia.
- Prolonged opioid use.
- Patients unable to be assessed using the Visual Analogue Scale (VAS) or unable to operate the Patient-Controlled Analgesia (PCA) device.
- Patients who refuse to participate in the study.
Who the study is looking for
- Patients aged 30-59 years.
- Patients with ASA physical status classification I-III.
- Patients with Body Mass Index (BMI) between 18 and 25 kg/m
Age in the registry: 30 years to 59 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Prof. Dr. I.G.N.G Ngoerah Central General Hospital Coordinator of this site? Confirm its status | Denpasar | Indonesia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.