NCT07274735Recruiting
Combined Effects of INF and OEP in Patients With Diabetic Peripheral Neuropathy
Combined Effect Of Intraneural Facilitation Therapy And Otago Exercise On Pain, Balance And Quality Of Life In Patients With Diabetic Peripheral Neuropathy
Source: ClinicalTrials.gov · Last updated 10 Dec 2025
Brief summary (registry, in English)
DPN often leads to balance issues, sensory deficits, and chronic pain, which can severely impact daily functioning and independence. INF therapy aims to improve nerve blood flow and alleviate neuropathic symptoms through manual techniques, while the Otago Exercise Program focuses on enhancing strength and balance to reduce fall risk. By comparing these two interventions, this study seeks to identify effective strategies that can improve balance, reduce pain, and enhance the quality of life for individuals suffering from DPN
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 65 (estimated)
- First submitted
- 28 Nov 2025
- Start date
- 17 Oct 2024
- Primary completion date
- 17 Jan 2026
- Lead sponsor
- Riphah International University
- NCT number
- NCT07274735
What you commit to
- Study type: Interventional
- Planned participants: 65
- From 17 Oct 2024 to the primary completion date, 17 Jan 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with documented active alcohol or drug misuse
- Patient with active inflammations or other inflammatory neuropathies including chronic inflammatory demyelinating polyneuropathy, proximal diabetic neuropathy, chemotherapy-induced peripheral neuropathy, autonomic neuropathies, or other neuropathies not associated with DM such as B12 deficiency
Other illness
- Patient with presence of any other systemic disease rather than diabetes such as end-stage renal failure, uncontrolled hypertension, severe dyslipidemia, chronic liver disease, autoimmune disease, advanced chronic obstructive pulmonary disease etc
Other
- Patient with total or partial amputation of lower extremities
- Participants will be also excluded if they were morbidly obese or if pregnant (self-reported)
Who the study is looking for
- Age 50-75years
- Both male and female patients will be included in the study
- Patient with type 2 diabetes mellitus (diagnosed by the physician)
- Patients with a score ≥ 4 on DN4 scale
- Patients have a score on the Timed Up-and-Go (TUG) test of less than 15 s
- Able to walk at least 10 meters long
Age in the registry: 50 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rasheed Hospital Coordinator of this site? Confirm its status | Lahore | Pakistan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.