NCT07279207Not yet recruiting
PACE-AF: Prospective Analysis of Cardiac Electrostimulation and Atrial Fibrillation
Prospective Analysis of Cardiac Electrostimulation and Atrial Fibrillation (PACE-AF)
Source: ClinicalTrials.gov · Last updated 12 Dec 2025
Brief summary (registry, in English)
PACE-AF is a prospective, observational patient registry designed to evaluate the impact of pacemaker algorithms on atrial fibrillation (AF) incidence, progression, and clinical outcomes in patients implanted with dual-chamber pacemakers. The registry aims to include 400-500 patients with longitudinal follow-up. Primary outcomes are progression to permanent AF and all-cause mortality. Secondary outcomes include quality of life, hospitalization, and cardiovascular events.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 500 (estimated)
- First submitted
- 19 Nov 2025
- Start date
- Dec 2025
- Primary completion date
- Dec 2027
- Lead sponsor
- Ilya Lukin
- Diseases
- Atrial fibrillation
- NCT number
- NCT07279207
What you commit to
- Study type: Observational
- Planned participants: 500
- From Dec 2025 to the primary completion date, Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- • Single-chamber pacemaker or Cardiac Resynchronization Therapy device at baseline
- Life expectancy \< 1 year due to non-cardiac comorbidities
- Inability to comply with follow-up visits or device interrogation
- Participation in another clinical trial that could interfere with study endpoints
Who the study is looking for
- • Age ≥ 18 years
- Implantation of a dual-chamber permanent pacemaker
- Ability to provide informed consent
- Willingness to participate in long-term follow-up
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tver State Medical University Clinical Center Coordinator of this site? Confirm its status | Tver' | Russia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.