NCT07280559Not yet recruiting
Evaluation of AI-assisted LDCT Screening in Lung Cancer
Evaluation of AI Medical Software-assisted LDCT Interpretation in Lung Cancer Screening and Prognosis: a Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 12 Dec 2025
Brief summary (registry, in English)
This multicenter pragmatic randomized controlled trial evaluates whether AI-assisted interpretation of low-dose CT (LDCT) improves lung cancer screening performance compared with standard reading. Eligible participants are randomized to AI-assisted or conventional interpretation. The study assesses diagnostic accuracy, efficiency, lung cancer incidence, mortality, recurrence, and smoking cessation outcomes. Results will inform the clinical utility and potential implementation of AI-assisted LDCT in routine screening practice.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 1120 (estimated)
- First submitted
- 26 Nov 2025
- Start date
- 11 Dec 2025
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Taipei Veterans General Hospital, Taiwan
- Diseases
- Lung cancer
- NCT number
- NCT07280559
What you commit to
- Study type: Interventional
- Planned participants: 1120
- From 11 Dec 2025 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Chest CT or other higher-radiation chest imaging within the past 12 months.
- Inability to undergo thoracic puncture or surgery.
Other illness
- Individuals holding a major illness certificate for lung cancer.
- History of lung cancer within the past three years.
Age
- Presence of other severe diseases with an expected life expectancy \<5 years.
Other
- Pregnant women.
- Inability to hold breath or otherwise complete the scanning procedure.
- Hemoptysis of unknown cause within the past month.
- Chest X-ray within the past month showing suspicious lung lesions.
- Unexplained weight loss \>6 kg within the past year.
Who the study is looking for
- Family History of Lung Cancer: Males aged 45-74 or females aged 40-74 with first-degree relatives (parents, siblings, or children) diagnosed with lung cancer.
- Heavy Smoking History: Ages 50-74 with ≥20 pack-years smoking history, currently smoking or quit \<15 years ago.
- General Screening Participants: Adults aged 40 years or older attending routine health check-ups.
Age in the registry: 40 years to 74 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Taipei Veterans General Hospital Coordinator of this site? Confirm its status | Taipei | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.