NCT07282106Completed
Effect of Transcutaneous Auricular Stimulation of the Vagus Nerve on Functional Connectivity in the Brain at Rest
Effect of Transcutaneous Auricular Stimulation of the Vagus Nerve on Functional Connectivity in the Brain at Rest: fNIRS Study in Chronic Post-stroke Subjects and Healthy Subjects
Source: ClinicalTrials.gov · Last updated 17 Mar 2026
Brief summary (registry, in English)
The goal of this clinical trial is to study the effect of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on resting-state brain functional connectivity. The study will assess this effect using functional Near-Infrared Spectroscopy (fNIRS) in both chronic post-stroke patients and healthy subjects. The main questions it aims to answer are: Does taVNS affect resting-state functional connectivity (measured by fNIRS) in chronic post-stroke patients? Does taVNS affect resting-state functional connectivity (measured by fNIRS) in healthy subjects? Are there differences in the effect of taVNS on functional connectivity between the post-stroke group and the healthy group? Researchers will compare the effect of active taVNS (real stimulation) to a sham stimulation (control) to evaluate its specific impact on the brain's functional networks.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 84 (actual)
- First submitted
- 1 Dec 2025
- Start date
- 8 Dec 2025
- Primary completion date
- 5 Feb 2026
- Lead sponsor
- Clinique Les Trois Soleils
- Diseases
- Stroke
- NCT number
- NCT07282106
What you commit to
- Study type: Interventional
- Participants enrolled: 84
- From 8 Dec 2025 to the primary completion date, 5 Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Allergy to neoprene (the material used to make the fNIRS cap);
- Cognitive impairment making it impossible to participate in the study;
- Phasic disorders preventing understanding of instructions and effective communication;
- Allergy to neoprene (the material used to make the fNIRS cap);
Other
- Hair volume preventing the cap from being put on and/or access to the scalp;
- Pregnant or breastfeeding women;
- Persons under legal protection
- Hair volume preventing the cap from being put on and/or access to the scalp;
- Pregnant or breastfeeding women;
- Persons under legal protection
Who the study is looking for
- age 18 or older
- Right-handed participant;
- Hemiparesis in the chronic phase (\>6 months post-stroke)
- Participant who has agreed to sign an informed consent form;
- Participant who is affiliated with social security.
- age 18 or older
- Right-handed participant;
- Participant who has agreed to sign an informed consent form;
- Participant who is affiliated with social security.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clinique Les Trois Soleils Coordinator of this site? Confirm its status | Boissise-le-Roi | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.