NCT07283419Completed
Predictors of rTMS and Group Therapy Efficacy in Adolescent Depression
Family Environment and Cognitive Function as Predictors of Efficacy for rTMS Combined With Group Therapy in Adolescent Depression: A Prospective Cohort Study
Source: ClinicalTrials.gov · Last updated 15 Dec 2025
Brief summary (registry, in English)
This study aims to identify baseline predictors of treatment efficacy in adolescents with Major Depressive Disorder (MDD) undergoing a combined intervention of repetitive transcranial magnetic stimulation (rTMS) and group therapy. Specifically, the study investigates the predictive value of family environment characteristics (cohesion, conflict, expressiveness) and cognitive functions (executive function, attention/inhibition).
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 163 (actual)
- First submitted
- 2 Dec 2025
- Start date
- 1 Aug 2023
- Primary completion date
- 31 Jul 2024
- Lead sponsor
- The First Hospital of Hebei Medical University
- Diseases
- Depression
- NCT number
- NCT07283419
What you commit to
- Study type: Observational
- Participants enrolled: 163
- From 1 Aug 2023 to the primary completion date, 31 Jul 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Receiving concurrent formal psychotherapy outside the study protocol.
Other illness
- Lifetime diagnosis of a psychotic or bipolar disorder.
- Current substance use disorder.
- Significant neurological illness (e.g., epilepsy) or metallic implants contraindicated for rTMS.
Who the study is looking for
- Primary diagnosis of Major Depressive Disorder (MDD) according to ICD-10 criteria.
- Score of ≥ 20 on the 24-item Hamilton Depression Rating Scale (HAMD-24).
- Sufficient intellectual and linguistic ability to complete assessments and participate in therapy.
- Provided written informed consent (participants and guardians).
Age in the registry: 12 years to 18 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Hospital of Hebei Medical University Coordinator of this site? Confirm its status | Shijiazhuang | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.