NCT07284082Recruiting
The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in Women
Source: ClinicalTrials.gov · Last updated 22 Apr 2026
Brief summary (registry, in English)
Menopause is associated with the acceleration of many comorbidities, including cardiovascular disease. Whether HIV and menopause together increase cardiovascular disease risk is a key knowledge gap. The goal of this observational study is to address this knowledge gap by looking at the role of menopause on cardiovascular disease risk factors such as insulin resistance, hypertension, hyperlipidemia, and carotid atherosclerosis using previously collected data. The investigators will look at underlying causes for cardiovascular diseases worsening in menopausal women with HIV by looking at the role of increased inflammation in the body and whether this is altered by weight. The investigators achieve this by enrolling participants who are willing to undergo a whole body MRI.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 90 (estimated)
- First submitted
- 10 Dec 2025
- Start date
- 17 Apr 2026
- Primary completion date
- 1 Mar 2030
- Lead sponsor
- University of California, San Francisco
- Diseases
- HIV
- NCT number
- NCT07284082
What you commit to
- Study type: Observational
- Planned participants: 90
- From 17 Apr 2026 to the primary completion date, 1 Mar 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Women who are not on antiretroviral therapy
- Women who are receiving treatment for active cancer or tuberculosis
Other illness
- Women who are not virally suppressed (HIV RNA \>200 copies/mL)
- Women who have a history of hysterectomy or oophorectomy
Who the study is looking for
- 90 non-pregnant women with HIV (approximately 30 in each menopausal phase) from the San Francisco MWCCS site.
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of California San Francisco Coordinator of this site? Confirm its status | San Francisco | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.