NCT07285356Recruiting
Study to Evaluate the Use of Surgical Gloves for the Prevention of Oxaliplatin-Induced Peripheral Neuropathy
GLOX-PEN: Phase II Clinical Trial to Evaluate the Use of Surgical Gloves for the Prevention of Oxaliplatin-Induced Peripheral Neuropathy
Source: ClinicalTrials.gov · Last updated 16 Dec 2025
Brief summary (registry, in English)
The primary objective of this randomized clinical trial is to assess whether the use of surgical gloves during treatment can prevent the occurrence of oxaliplatin-induced peripheral neuropathy.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 84 (estimated)
- First submitted
- 17 Nov 2025
- Start date
- 6 Oct 2025
- Primary completion date
- 18 Sept 2026
- Lead sponsor
- AC Camargo Cancer Center
- Diseases
- Colorectal cancer
- NCT number
- NCT07285356
What you commit to
- Study type: Interventional
- Planned participants: 84
- From 6 Oct 2025 to the primary completion date, 18 Sept 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior treatment with paclitaxel, docetaxel or oxaliplatin.
Other illness
- Uncontrolled diabetes.
- known glove allergies.
Other
- Pre-existing neuropathy.
Who the study is looking for
- Patients aged 18 years or older who have provided written informed consent.
- Colon adenocarcinoma with high-risk stage III (pT4pN2) or stage IV.
- Oxaliplatin-based treatment in the context of localized or metastatic disease.
- Eastern Cooperative Oncology Group (ECOG) performance status of 0-1.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| A.C. Camargo Cancer Center Coordinator of this site? Confirm its status | São Paulo | Brazil | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.