NCT07286435Recruiting
The Effect of Whole-Body Vibration Therapy Following Botulinum Toxin A Injection on Spasticity and Balance in Stroke Patients
Source: ClinicalTrials.gov · Last updated 3 Sept 2026
Brief summary (registry, in English)
The purpose of this clinical study is to evaluate the effect of Whole Body Vibration (WBV) therapy, applied two weeks after botulinum toxin type A (BoNT-A) injection, on spasticity and balance parameters in individuals with stroke who have ankle spasticity. The main questions it aims to answer are: Adjuvant WBV therapy administered after BoNT-A injection; * Does it effectively improve spasticity? * Is it an effective intervention for balance and walking functions? Researchers will compare the application of WBV to a placebo application (a vibration-free application) to evaluate the effect of adjuvant WBV therapy administered after BoNT-A injection on ankle spasticity, balance, and walking function in individuals with stroke.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 2 Dec 2025
- Start date
- Jan 2026
- Primary completion date
- Jun 2027
- Lead sponsor
- Uludag University
- Diseases
- Stroke
- NCT number
- NCT07286435
What you commit to
- Study type: Interventional
- Planned participants: 50
- From Jan 2026 to the primary completion date, Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participants whose antispasmodic medication regimen was changed within 1 month prior to starting treatment
Other illness
- History of neurological disease (such as polyneuropathy or motor neuron diseases) other than a history of existing stroke
- History of recent fracture in the lower extremity
- Severe degenerative joint disease
- History of implants in the lower extremity or spine
- History of cardiac pacemakers
- Presence of uncontrolled hypertension and uncontrolled diabetes
- History of recent thromboembolism or infection
Who the study is looking for
- Participants with unilateral hemiparesis due to hemorrhage or infarction
- Participants aged 18-75 years
- Participants with MAS ≥2 spasticity in the ankle
- Participants with a Mini-Mental State Examination (MMSE) score of 24, indicating preserved cognitive and communication abilities
- Participants who can walk at least 100 meters with or without assistive devices
- Participants without joint contractures and with sufficient motor control to perform functional walking tests
- Participants who have not previously undergone vibration therapy
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Bursa Uludağ University Faculty of Medicine Coordinator of this site? Confirm its status | Bursa | Turkey (Türkiye) | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.