NCT07289750Not yet recruitingPhase 4
The Effect of Alogliptin Combined With Actoplus Met on Glucose and Lipid Metabolism and Pancreatic Function in Patients With T2DM Complicated With MAFLD
The Effect of Alogliptin Combined With Pioglitazone and Metformin Hydrochloride Tablets on Glucose and Lipid Metabolism and Islet Function in Patients With Type 2 Diabetes Mellitus Complicated With Metabolic Dysfunction-associated Fatty Liver Disease
Source: ClinicalTrials.gov · Last updated 24 Mar 2026
Brief summary (registry, in English)
To compare the efficacy and safety of the combination of alogliptin and actoplus met with that of actoplus met alone in improving the glucose and lipid metabolism and pancreatic function in T2DM patients complicated with MAFLD.
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 80 (estimated)
- First submitted
- 4 Dec 2025
- Start date
- May 2026
- Primary completion date
- Aug 2027
- Lead sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
- NCT number
- NCT07289750
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 80
- From May 2026 to the primary completion date, Aug 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe infections, surgeries and other emergency
- Other types of diabetes
- Severe cardiovascular, brain, liver and kidney disorders
- Malignant tumor
Who the study is looking for
- Clinical diagnosis of T2DM
- Clinical diagnosis of MAFLD
- HbA1c: 6.5-9.5%
- BMI: 19-35 kg/m2
- No hypoglycemic drugs or insulin have been used within half a year
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.