NCT07293728Not yet recruitingPhase 4
A Randomized Feasibility Trial Comparing Drospirenone and Norethindrone for Postpartum Hypertension Management in Preeclampsia
Source: ClinicalTrials.gov · Last updated 19 Dec 2025
Brief summary (registry, in English)
This is an open-label, randomized feasibility trial in which patients admitted to Oregon Health \& Science University (OHSU) after a pregnancy complicated by preeclampsia who are considering a progestin-only pill contraception postpartum will be randomized to norethindrone or drospirenone for 6 weeks following hospital discharge.
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 17 Dec 2025
- Start date
- Jul 2026
- Primary completion date
- Dec 2026
- Lead sponsor
- Oregon Health and Science University
- Diseases
- High blood pressure
- NCT number
- NCT07293728
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 50
- From Jul 2026 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Planned use of a contraceptive method other than a progestin-only pill
- Contraindications to drospirenone or norethindrone
- Inability to monitor blood pressure at home after discharge
- Inability to complete follow-up surveys by email in English
Who the study is looking for
- Admission to Oregon Health \& Science University following a birth (during the same admission)
- A diagnosis of preeclampsia or chronic hypertension with superimposed preeclampsia (with or without severe features)
- Considering use of a progestin-only pill for postpartum contraception
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Oregon Health Science University Coordinator of this site? Confirm its status | Portland | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.