NCT07295002Not yet recruiting
Sentinel Node Resection With or Without LECS After Noncurative ESD for EGC
COmpletion Sentinel Node Resection With or Without Minimally invAsive and Endoscopic Cooperative Surgery Following noncuRative Endoscopic Submucosal Dissection for Early Gastric Cancer
Source: ClinicalTrials.gov · Last updated 19 Dec 2025
Brief summary (registry, in English)
For patients with non-curative resection after endoscopic submucosal dissection (ESD) for early gastric cancer (EGC), complementary surgery is generally recommended. However, about 2/3 of patients have no remaining tumor in the stomach or regional lymph nodes. In this trial, Indocyanine Green (ICG)-guided lymphadenectomy with or without laparoscopic and endoscopic cooperative surgery (LECS) will be tested as a less invasive alternative in such cases. For patients with a primary radically resected EGC, ICG-guided lymphadenectomy alone will be performed. For patients with deep-margin positive EGC, ICG-guided lymphadenectomy and LECS will be performed, in order to ensure both local tumor control in the stomach and in regional nodes.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 10 (estimated)
- First submitted
- 15 Nov 2025
- Start date
- Jan 2026
- Primary completion date
- Oct 2029
- Lead sponsor
- Region Stockholm
- Diseases
- Gastric and esophageal cancer
- NCT number
- NCT07295002
What you commit to
- Study type: Interventional
- Planned participants: 10
- From Jan 2026 to the primary completion date, Oct 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Non-curative resection with only non-radicality horizontal margin
- Previous radiotherapy to the upper abdomen
Other illness
- Allergy to ICG
- Inability to provide informed consent due to cognitive impairment, language barrier, or other reasons impairing understanding and autonomous decision-making.
Other
- Location within 2 cm from cardia or pylorus
- Inoperative because of severe comorbidities
- Pregnancy
Who the study is looking for
- EGC previously treated with ESD according to current guidelines (differentiated adenocarcinoma, not ulcerative, of any size, differentiated adenocarcinoma ulcerative \</=3cm, undifferentiated adenocarcinoma not ulcerative \</=2cm)
- Non curative resection
- Lymphovascular invasion
- Non-radical resection vertical margin
- deep submucosal invasion
- Signed informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Karolinska University Hospital Huddinge Coordinator of this site? Confirm its status | Stockholm | Sweden | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.