NCT07295990Recruiting
Tongue-strengthening Exercises in People With ALS.
The Impact of Dysphagia Exercise on Oropharyngeal Swallowing Function in Patients With ALS
Source: ClinicalTrials.gov · Last updated 12 Aug 2026
Brief summary (registry, in English)
This study is testing a tongue exercise program for people living with ALS to see if it can help support speech and swallowing. All participants will receive the treatment, and researchers will measure changes over time by comparing each person's results to their own earlier results. People who join the study will have two in-person visits and four weekly telehealth sessions with a speech-language pathologist. During these sessions, participants will practice tongue resistance exercises, complete speech and swallowing tasks, and answer surveys about their experience. They will also use a small device at home to measure tongue strength and swallowing. The exercise program involves pressing the tongue against a device several times a day, five days per week, for five weeks. Researchers want to learn if this program is safe, practical, and helpful for people with ALS.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 3 Dec 2025
- Start date
- 1 May 2026
- Primary completion date
- Dec 2028
- Lead sponsor
- Nova Southeastern University
- Diseases
- ALS (motor neurone disease)
- NCT number
- NCT07295990
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 1 May 2026 to the primary completion date, Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Other concomitant neurogenic disorder
- Recent oral surgery other than routine dental surgery
Other illness
- Stroke
- Head and neck cancer
Other
- Head injury
- Tracheostomy
- Unable to generate isometric lingual pressure on lingual manometer
- Participation in another clinical trial intervention that may confound results
- NPO (nothing by mouth)
- Anarthric
Who the study is looking for
- Diagnosis of possible, probable, or definite ALS (El-Escorial Revisited)
- Lingual exercises naïve
- Impaired lingual strength generation compared to normative data
- EAT-10 score \<3
Age in the registry: 18 years to 99 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Nova Southeastern University Coordinator of this site? Confirm its status | Davie | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.