NCT07296146CompletedPhase 3
Probiotics Against Erythropoietin Resistance in Chronic Kidney Disease Patients.
Effect of Probiotic Supplementation on Resistant Anaemia to Erythropoietin in Chronic Kidney Disease Patients.
Source: ClinicalTrials.gov · Last updated 30 Oct 2026
Brief summary (registry, in English)
The goal of this clinical trial is to assess whether probiotic supplementation can improve the hematological response of CKD patients to erythropoietin therapy and prevent or reduce erythropoietin resistance. The main questions it aims to answer are: Can probiotic be used as an adjuvant strategy in anemia management and increasing ESA responsiveness in CKD? What medical problems do participants have when taking probiotic? Researchers will compare Erythropoietin only with Erythropoietin + Probiotic to see if Probiotic aids in treating anaemic chronic kidney disease patients. Participants will: Take Erythropoietin + Probiotic or Probiotic only every day for 3 months Visit the clinic once every 4 weeks for checkups and tests Keep a diary of their symptoms
- Status (registry)
- Completed
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 80 (actual)
- First submitted
- 19 Nov 2025
- Start date
- 1 Feb 2026
- Primary completion date
- 1 Aug 2026
- Lead sponsor
- Badr University
- Diseases
- Chronic kidney disease
- NCT number
- NCT07296146
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 80
- From 1 Feb 2026 to the primary completion date, 1 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent probiotic, antibiotic, or immunosuppressive therapy
Other illness
- Recent or planned kidney transplantation Gastrointestinal disorders (active IBD, cancer)
- Severe comorbidities (e.g., active infection, malignancies)
Other
- Microcytic hypochromic anemia.
- Patients with hyperparathyroidism
- Pregnancy or lactation
- Cognitive or physical inability to comply with protocol
Who the study is looking for
- Adult patients with end stage renal disease for more than 3 months on regular hemodialysis (GFR less than 15 ml/min/m2
- Receiving stable doses of erythropoietin therapy
- Able and willing to provide informed consent
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Badr University Hospital Coordinator of this site? Confirm its status | Cairo | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.