NCT07297407Recruiting
Prevention-in-PD-Study
PREVENTION-IN-PD - Development of a Multidomain Lifestyle Intervention Study for Prodromal and Clinical Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 15 Oct 2026
Brief summary (registry, in English)
The goal of this clinical trial (feasibility study) is to learn if a multimodal lifestyle program can improve adherence to recommended lifestyle changes in people with REM Sleep Behavior Disroder (RBD) or Parkinson's disease (PD). The main question it aims to answer is if individuals with RBD oder PD can follow a combined lifestyle program over six months Participants will take part in a six-month intervention program that includes: Physical training, Mediterranean diet counseling, Sleep counseling and cognitive training. The program will be supported by psychoeducation, skills training, and personalization to make it practical and motivating.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 99 (estimated)
- First submitted
- 16 Sept 2025
- Start date
- 1 Apr 2026
- Primary completion date
- Sept 2027
- Lead sponsor
- University Hospital Schleswig-Holstein
- Diseases
- Parkinson disease
- NCT number
- NCT07297407
What you commit to
- Study type: Interventional
- Planned participants: 99
- From 1 Apr 2026 to the primary completion date, Sept 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Planned change in medication within the following 6 months
Other illness
- dementia (Mini Mental Score, MMSE \< 19 points) (MMSE is specifically chosen here to avoid too frequent repetitions of the MoCA, which is used as an outcome parameter for the interventional trial)
- other significant diseases of the central nervous system
Other
- physical inability to perform exercise training or other trainings as judged by a physician
- manifest (severe) depression (Beck Depression Inventory, BDI-II \> 29 points)
- participation in other interventional trials
Who the study is looking for
- All participants: ability to perform informed consent; age 30-85
- RBD group: polysomnographic proven diagnosis of isolated REM sleep behavior disorder (iRBD)
- PD group: early to moderate disease (Hoehn \& Yahr stage 1-2.5), diagnosis according to the Movement Disorder Society diagnostic criteria for clinical Parkinson's Disease
- Agreement to participate in group sessions and online meetings
Age in the registry: 30 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital of Schleswig Holstein Campus Kiel Coordinator of this site? Confirm its status | Kiel | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.