NCT07299071Recruiting
Efficacy of CAD in Screening Colonoscopy to Reduce the Risk of Advanced Adenoma at 3 Years.
Randomized Controlled Trial Evaluating the Efficacy of CAD in Screening Colonoscopy to Reduce the Risk of Advanced Adenoma at 3 Years.
Source: ClinicalTrials.gov · Last updated 24 Sept 2026
Brief summary (registry, in English)
The occurrence of interval cancers after colonoscopy raises the possibility of missed lesions. High- performance computer aided diagnosis (CAD) systems have been specially designed for the detection of colorectal lesions (CAD for detection is named CADe). The use of CADe improves adenoma detection in screening colonoscopy. The potential of CADe system in reducing the rate of progression to advanced polyps or interval cancer between two colonoscopies remains still uncertain.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 592 (estimated)
- First submitted
- 9 Dec 2025
- Start date
- Mar 2026
- Primary completion date
- Mar 2031
- Lead sponsor
- University Hospital, Bordeaux
- Diseases
- Colorectal cancer
- NCT number
- NCT07299071
What you commit to
- Study type: Interventional
- Planned participants: 592
- From Mar 2026 to the primary completion date, Mar 2031
- 15 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- An infiltrative tumor was diagnosed during colonoscope insertion time, not accessible to endoscopic resection and likely to require surgical management (a procedure where part of the colon may need to be removed).
Other illness
- Personal history of inflammatory bowel disease
- Personal history of genetic predisposition of CRC
- Personal history of major colorectal surgery involving total or subtotal colectomy
Other
- Failed complete colonoscopy, defined by the absence of cecal intubation or identification of the terminal ileum.
- Inadequate bowel preparation (Boston bowel preparation score \< 6, and/or least at one part of colon with score ≤ 1)
- Patient under guardianship or protection
- Pregnant women
- Not fluent in French or illiterate
Who the study is looking for
- Patients over 18 years of age with indication for colonoscopy as part of a screening program, after a positive immunological (FIT) test, and/or for personal or family history of colorectal cancer and/or personal history of colonic adenomas and/or sessile serrated polyp,
- Written informed consent signed
- Patients covered by a health-care insurance.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (15)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CH de la côte Basque Coordinator of this site? Confirm its status | Bayonne | France | Not yet recruiting |
| CHU Brest la Cavale Blanche Coordinator of this site? Confirm its status | Brest | France | Not yet recruiting |
| Hôpital de Carhaix Coordinator of this site? Confirm its status | Carhaix-Plouguer | France | Not yet recruiting |
| Clinique Paris Bercy Coordinator of this site? Confirm its status | Charenton-le-Pont | France | Not yet recruiting |
| CHU de Limoges Coordinator of this site? Confirm its status | Limoges | France | Not yet recruiting |
| Institut Paoli-Calmettes Coordinator of this site? Confirm its status | Marseille | France | Not yet recruiting |
| Clinique Jules Verne Coordinator of this site? Confirm its status | Nantes | France | Not yet recruiting |
| CHU Nîmes Coordinator of this site? Confirm its status | Nîmes | France | Not yet recruiting |
| Aphp Hegp Coordinator of this site? Confirm its status | Paris | France | Not yet recruiting |
| APHP - Hôpital Saint Antoine Coordinator of this site? Confirm its status | Paris | France | Not yet recruiting |
| APHP - Hôpital Tenon Coordinator of this site? Confirm its status | Paris | France | Not yet recruiting |
| CHU Bordeaux - Hopital Haut-Leveque Coordinator of this site? Confirm its status | Pessac | France | Recruiting |
| CHU de Rennes Coordinator of this site? Confirm its status | Rennes | France | Not yet recruiting |
| Clinique Pasteur Coordinator of this site? Confirm its status | Toulouse | France | Not yet recruiting |
| CHRU de Nancy - Hôpital Brabois Adultes Coordinator of this site? Confirm its status | Vandœuvre-lès-Nancy | France | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.