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NCT07299084Active, not recruitingPhase 1

A Study to Evaluate the Effect of Fasting Duration and Tirzepatide Withholding on the Amount of Food and Fluid in the Stomach in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes Mellitus

A Study to Evaluate the Effect of Fasting Duration and Temporary Withholding of Tirzepatide on Retained Gastric Contents Using Gastric Ultrasound in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes Mellitus

Source: ClinicalTrials.gov · Last updated 19 May 2026

Brief summary (registry, in English)

The purpose of this study is to evaluate how fasting and stopping the use of tirzepatide affects the amount of food and drink that stays in the stomach after a meal. Ultrasound will be used to check the stomach content after a test meal.

Status (registry)
Active, not recruiting
Phase (registry)
Phase 1
Study type
Interventional
Enrollment
40 (estimated)
First submitted
10 Dec 2025
Start date
14 Jan 2026
Primary completion date
30 Nov 2026
Lead sponsor
Eli Lilly and Company
NCT number
NCT07299084

What you commit to

  • Study type: Interventional · Phase 1
  • Planned participants: 40
  • From 14 Jan 2026 to the primary completion date, 30 Nov 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Have had weight loss surgery

Other illness

  • Have a condition that affects how their stomach empties
  • Have type 1 diabetes
  • Have any major medical conditions or histories that could interfere with the study

Who the study is looking for

  • Meet one of the following criteria:
    • Have type 2 diabetes
    • Have obesity
    • Have overweight with at least one health issue related to weight but without type 2 diabetes

Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Lilly Centre for Clinical Pharmacology
Coordinator of this site? Confirm its status
SingaporeSingaporeUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.