Sign in

NCT07299162Recruiting

The Effect of Virtual Reality Therapy on Upper Extremity Functions in Subacute Stroke Patients Receiving Rehabilitation

The Effect of Virtual Reality Therapy on Upper Extremity Functions in Subacute Stroke Patients Receiving Conventional Rehabilitation and Action Observation Therapy: A Randomized Controlled Single-Blind Study

Source: ClinicalTrials.gov · Last updated 28 Jan 2026

Brief summary (registry, in English)

Stroke ranks second among the leading causes of death worldwide and third among the causes of disability. In stroke patients, motor impairment typically affects facial movements and the upper and lower extremities unilaterally. Upper extremity involvement, in particular, negatively impacts patients' activities of daily living, such as eating and dressing. Various rehabilitation methods are used to improve the function of the paretic upper extremity in stroke patients. Action Observation Therapy and Virtual Reality are among the rehabilitation approaches currently used to support upper extremity rehabilitation. In our study, patients will be randomly divided into two groups: one group will receive conventional rehabilitation and Action Observation Therapy, while the other group will additionally receive Virtual Reality therapy. This study aims to investigate the contribution of Virtual Reality therapy, when added to conventional rehabilitation and Action Observation Therapy, to the recovery of the paretic upper extremity in patients with subacute stroke.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
38 (estimated)
First submitted
25 Nov 2025
Start date
15 Aug 2025
Primary completion date
25 Mar 2026
Lead sponsor
Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Diseases
Stroke
NCT number
NCT07299162

What you commit to

  • Study type: Interventional
  • Planned participants: 38
  • From 15 Aug 2025 to the primary completion date, 25 Mar 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • History of bilateral stroke
  • Patients with global aphasia and/or cognitive impairment that significantly affects treatment compliance
  • Patients with severe visual impairment

Other

  • Presence of pain in the paretic shoulder severe enough to prevent exercise
  • Presence of unilateral spatial neglect
  • Inability to maintain sitting balance
  • Modified Ashworth Scale \> 4 in the hemiplegic arm

Who the study is looking for

  • Patients over the age of 18
  • Patients in the subacute phase of stroke (between 6 weeks and 6 months post-stroke)
  • Patients with a first-ever stroke
  • Brunnstrom stage 3 or above for both upper extremity and hand
  • Mini-Mental State Examination (MMSE) score \>=20
    • No major medical condition that would prevent participation in the treatment

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
İstanbul Physical Therapy and Rehabilitation Training and Research Hospital
Coordinator of this site? Confirm its status
IstanbulTurkey (Türkiye)Recruiting

This page is information, not medical advice. Discuss any trial with your doctor.