NCT07299318Not yet recruiting
Multimodal Deep Learning for Lymph Node Metastasis in Thyroid Cancer
A Multicenter Study on Developing a Multimodal Deep Learning Model Based on Color Doppler Ultrasound for Predicting Lymph Node Metastasis and Cancer Staging in Papillary Thyroid Carcinoma
Source: ClinicalTrials.gov · Last updated 23 Dec 2025
Brief summary (registry, in English)
Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy in clinical practice, accounting for approximately 85% of all thyroid malignancies. The occurrence of cervical lymph node metastasis further increases the risk of local tumor recurrence and distant metastasis, thereby reducing patient survival rates. Pathological examinations reveal that approximately 30-80% of PTC patients have lymph node metastasis. Early detection of metastatic lymph nodes and the development of individualized treatment plans are crucial for improving patient prognosis. Currently, the primary method for diagnosing lymph node metastasis is ultrasound-guided fine-needle aspiration, but its accuracy is limited by sample quality and carries a risk of false-negative results. In recent years, deep learning technology has demonstrated significant potential in the field of medical image analysis. Therefore, the investigators aim to develop a deep learning model based on neck ultrasound to more accurately predict lymph node metastasis.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 3200 (estimated)
- First submitted
- 9 Dec 2025
- Start date
- 1 Jan 2026
- Primary completion date
- 1 Mar 2026
- Lead sponsor
- West China Hospital
- Diseases
- Thyroid cancer
- NCT number
- NCT07299318
What you commit to
- Study type: Observational
- Planned participants: 3200
- From 1 Jan 2026 to the primary completion date, 1 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Cases aged \<18 years or \>80 years. Cases with poor-quality ultrasound images. Cases with incompletely visualized nodules. Cases with images showing multiple distinct lesions. Cases belonging to special populations. Cases with concurrent other tumors. Cases with a history of thyroid cancer resection
Who the study is looking for
- Cases aged 18-80 years who underwent thyroid ultrasound examination and postoperative pathological examination of the thyroid.
- Cases with a first-time diagnosis of papillary thyroid carcinoma. Cases who underwent lymph node dissection
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| West China Hospital of Sichuan University Coordinator of this site? Confirm its status | Chengdu | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.