NCT07300332Recruiting
Exercise Training and Vitamin D Metabolism
The Impact of Hybrid-type High-intensity Interval Training on Vitamin D Metabolism in Adults With Overweight/Obesity
Source: ClinicalTrials.gov · Last updated 26 May 2026
Brief summary (registry, in English)
The prevalence of Vitamin D deficiency is significantly higher in adults with overweight/obesity compared to those with normal body mass index (BMI). The "entrapment" of Vitamin D in adipose tissue due to impaired lipolytic stimulation and/or adipose tissue dysfunction has been proposed as the driving mechanism. Exercise training has been proposed as a promising strategy to increase mobilization of Vitamin D from adipose tissue, given its well described role in stimulating lipolysis. Indeed, a recent study revealed that participation in moderate-intensity cardiovascular type exercise over winter can mitigate the decline in 25-hydroxyvitamin D \[25(OH)D\] in adults with overweight/obesity, independent of weight loss. The aim of this study is to investigate the impact of hybrid-type high-intensity interval training over winter on vitamin D metabolism, in adults with overweight/obesity.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 9 Dec 2025
- Start date
- 10 Nov 2025
- Primary completion date
- 31 Jan 2026
- Lead sponsor
- University of Thessaly
- Diseases
- Obesity
- NCT number
- NCT07300332
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 10 Nov 2025 to the primary completion date, 31 Jan 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Consumption of anti-inflammatory drugs, statins and/or steroids
Other
- Consumption of Vitamin D supplements
Who the study is looking for
- BMI = 25-35 kg/m2
- Absence of musculoskeletal injuries
- Absence of chronic health-related complications
- Non-smokers
Age in the registry: 35 years to 50 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Physical Education and Sport Science, University of Thessaly Coordinator of this site? Confirm its status | Trikala | Greece | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.