NCT07300852Not yet recruiting
DSLT in Normal Tension Glaucoma (NTG) Asian Eyes
The Effectiveness of DSLT in Asian Normal Tension Glaucoma Patients
Source: ClinicalTrials.gov · Last updated 24 Dec 2025
Brief summary (registry, in English)
The goal of this clinical trial is to evaluate the efficacy of direct selective laser trabeculoplasty (DSLT) or laser treatment in Asian patients with normal tension glaucoma. The main question it aims to answer is: Does the DSLT reduce intraocular pressure (IOP) and medication use in Asian NTG subjects? Participants will attend routine follow-up visits with their eye surgeon and glaucoma testing such as optical coherence tomography (OCT) imaging and visual field test(s) after the laser study treatment.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 9 Dec 2025
- Start date
- 1 Jan 2026
- Primary completion date
- 31 Jan 2028
- Lead sponsor
- Ngoc Nguyen Inc.
- Diseases
- Glaucoma
- NCT number
- NCT07300852
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 1 Jan 2026 to the primary completion date, 31 Jan 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients anticipating cataract surgery during the study follow-up period
Other illness
- History of SLT within last 2 years
- History intraocular surgery including refractive surgery, except for history of cataract surgery that has been greater than 1 year
- Any presence of relevant ocular diseases including retinal disease with no confirmed cure
Other
- Angle closure glaucoma or narrow angle status post laser peripheral iridotomy (LPI), or any other open angle glaucoma excluding NTG
- Unable to have DSLT procedure due to pre-limbal findings
Who the study is looking for
- Asian descent
- NTG diagnosis: glaucomatous optic neuropathy in patients with IOP measurements consistently lower than 21 mmHg
- Mean deviation (MD) of the visual field between 0 to -12dB
- No significant central vision loss within 5 degrees within 5th percentile
- Age ≥20 years
- NTG patients who are medically controlled on 1-3 medications and safe to wash out or IOP is still insufficient from medications and safe to washout
- Shaffer grade II or more on 3 of the 4 quadrants
- Central corneal thickness (CCT) 450-600µm
- All participants are able to provide written informed consent before participation
Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ngoc Nguyen M.D. Coordinator of this site? Confirm its status | San Jose | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.