NCT07302191Completed
High-Intensity Interval or Concurrent Exercise on Oxidative Stress and Inflammation in Obese Women
Comparable Reductions in Health Biomarkers Following High-Intensity Interval or Concurrent Training in Obese Postmenopausal Women
Source: ClinicalTrials.gov · Last updated 31 Dec 2025
Brief summary (registry, in English)
Introduction: Menopause is associated with body composition change, an increase in the cardio-metabolic risk factor for oxidative stress. Nevertheless, it has been suggested that regular physical training is an effective non-pharmacological intervention to reduce oxidative stress and cardio-metabolic disorders in menopausal individuals. Therefore, the present study was conducted to compare the effects of twelve weeks of high-intensity interval training (HIIT) and concurrent (Conc) and on body composition, cardio-metabolic indices and oxidative stress in sedentary obese postmenopausal women. Materials and methods: Forty-five menopausal obese women voluntarily participated and were randomly assigned into three groups: a) HIIT (6-12×60s of high intensity training (85-95% HRMax) and then running for 60 seconds with low intensity (55-60% HRMax)), b) concurrent endurance (performed on training with 55-75% HRMax) and strength training (including two sets in eight exercise stations with 55-75% 1RM)) and c) control group. Training programs were done for twelve weeks, 3 times per week. Body composition, cardio-metabolic indices and oxidative stress markers were measured before and after twelve weeks of exercise training program.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 58 (actual)
- First submitted
- 11 Dec 2025
- Start date
- 2 Sept 2025
- Primary completion date
- 20 Nov 2025
- Lead sponsor
- University of Valladolid
- Diseases
- Obesity
- NCT number
- NCT07302191
What you commit to
- Study type: Interventional
- Participants enrolled: 58
- From 2 Sept 2025 to the primary completion date, 20 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- hormone replacement therapy
Other illness
- diagnosed cardiovascular, renal, or hepatic disease, uncontrolled hypertension, or any musculoskeletal limitation precluding exercise participation
Other
- smoking.
Who the study is looking for
- Women with at least 12 months of amenorrhea.
- Physical abilities with the capacity to exercise safely as determined by a medical evaluation.
- Women in a sedentary state, defined as performing \<150 minutes of moderate to vigorous physical activity per week during the previous year.
- BMI \>25 and ≤40 kg/ m2
Age in the registry: 50 years to 65 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Faculty of Health Sciences, University of Valladolid Soria Campus, Soria, Soria 42004 Coordinator of this site? Confirm its status | Soria | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.