NCT07302737Not yet recruiting
Delirium and Heart Failure
Accuracy of Different Biomarkers for Predicting Delirium in Older Adults With Heart Failure
Source: ClinicalTrials.gov · Last updated 24 Dec 2025
Brief summary (registry, in English)
Biomarkers such as Systemic Immune-Inflammation Index (SII) and TG/Glucose Ratio (TyG) have shown promise in predicting delirium, reflecting the roles of inflammation and metabolic disturbances in its pathophysiology. This study aims to compare the predictive value of SII and the TyG ratio among other chemical and physiological biomarkers for diagnosing delirium and detecting its severity in older adults with heart failure. These biomarkers reflect different pathophysiological pathways implicated in delirium, including inflammation, cardiovascular stress, and metabolic dysfunction. By evaluating their individual and combined predictive abilities, this research seeks to identify potential tools for early identification of patients at high risk for delirium
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 4 Dec 2025
- Start date
- 20 Jan 2026
- Primary completion date
- 1 Jul 2026
- Lead sponsor
- Ain Shams University
- Diseases
- Heart failure
- NCT number
- NCT07302737
What you commit to
- Study type: Observational
- Planned participants: 100
- From 20 Jan 2026 to the primary completion date, 1 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Ongoing Treatment with Immunosuppressants, or corticosteroids
Other illness
- cognitive impairment
- Major Neurological Conditions: (e.g., stroke, traumatic brain injury).
Lab values
- Hematological diseases that affect platelet, neutrophil, and lymphocyte counts.
Other
- Cardiogenic Shock
- Sepsis
Who the study is looking for
- Heart failure stage C
Age in the registry: 60 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ain Shams University Hospitals Coordinator of this site? Confirm its status | Cairo | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.