NCT07303712Recruiting
Liquid Biopsy for Hepatocellular Carcinoma Molecular Characterization After Y90
Liquid Biopsy for Hepatocellular Carcinoma Molecular Characterization and Assessment of Treatment Response After Y90 Radioembolization: A Pilot Study
Source: ClinicalTrials.gov · Last updated 26 Dec 2025
Brief summary (registry, in English)
The purpose of this study is to determine if baseline liquid biopsy assays (CTC and cf-DNA) as well as single circulating tumor cell-DNA (sCTC DNA) dynamics in the early post-treatment period can predict subsequent treatment response to Y-90 radioembolization in patients with hepatocellular carcinoma (HCC).
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 12 (estimated)
- First submitted
- 17 Mar 2025
- Start date
- 1 Aug 2024
- Primary completion date
- 1 Aug 2026
- Lead sponsor
- Palo Alto Veterans Institute for Research
- Diseases
- Liver and biliary tract cancer
- NCT number
- NCT07303712
What you commit to
- Study type: Observational
- Planned participants: 12
- From 1 Aug 2024 to the primary completion date, 1 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior surgery or ablation on indicated tumors
Other
- Not eligible for Y90 procedure
- Patient unable to complete the follow up visits required for clinical care or research -
Who the study is looking for
- Age \> or = 18 years
- HCC confirmed on imaging, BCLC stage 0, A, B, or C
- Transarterial Y90 radioembolization approved by multidisciplinary tumor board -
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| VA Palo Alto Health Care System Coordinator of this site? Confirm its status | Palo Alto | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.