NCT07306962Recruiting
Virtual Lesion Segmentation and Mandibular Ameloblastoma Radiographic Safety Margin
Does Computer-assist Virtual Lesion Segmentation Ushers to a Change in the Literature Consensus Regarding Mandibular Ameloblastoma Radiographic Safety Margin?. A Clinical Case Series
Source: ClinicalTrials.gov · Last updated 29 Dec 2025
Brief summary (registry, in English)
Reconstruction of segmental mandibular defects is in a continuous state of evolution utilizing the recent advances in Computer-Aided Designing (CAD) and preoperative Virtual Surgical Planning (VSP). The anterior iliac crest is one of the ideal reservoirs for autogenous harvesting of a bi-cortical bone block with 1:1 cortical to cancellous bone ratio which is optimal for rapid and predictable consolidation. The aim of this study is the utility of VSP guided by CT and confirmation by histopathological analysis in achieving negative margins and preventing recurrence of mandibular ameloblastoma.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 10 (estimated)
- First submitted
- 13 Dec 2025
- Start date
- 1 Jan 2025
- Primary completion date
- 1 Dec 2026
- Lead sponsor
- Alexandria University
- Diseases
- Childhood cancers
- NCT number
- NCT07306962
What you commit to
- Study type: Interventional
- Planned participants: 10
- From 1 Jan 2025 to the primary completion date, 1 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with recurrent lesion after resection.
Other illness
- Patients with an active infection at the site of resection.
Other
- Patients with lateral segmental mandibular defect involving the condyle.
Who the study is looking for
- Patients with histologically confirmed ameloblastoma using a preoperative biopsy.
- Patients with ameloblastoma that require segmental mandibular continuity defect, not involving the condyle.
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Faculty of Dentistry, Alexandria University Coordinator of this site? Confirm its status | Alexandria | Egypt | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.