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NCT07310446Recruiting

Collection of Samples From the United States Population for Optimization and Evaluation of Colorectal Cancer (CRC) Plasma Circulating Free-DNA (cfDNA) Marker Panel Performance

Collection of Samples From the United States Population for Optimization and Evaluation of Colorectal Cancer (CRC) Plasma Circulating Free-DNA (cfDNA) Marker Panel Performance (PROVE)

Source: ClinicalTrials.gov · Last updated 30 Dec 2025

Brief summary (registry, in English)

This study is designed to prospectively collect blood samples and clinical data from patients that have been newly diagnosed with colorectal cancer and scheduled for resection surgery but are pre cancer treatment, subjects who are NOT scheduled for surgery but have histological confirmation of CRC from the diagnostic colonoscopy and clinical staging (cTMN) is available and are pr e- treatment, and patients who are at average risk of colorectal cancer and who are scheduled for routine colonoscopy examinations.

Status (registry)
Recruiting
Study type
Observational
Enrollment
6500 (estimated)
First submitted
1 Dec 2025
Start date
31 Jul 2023
Primary completion date
31 Dec 2026
Lead sponsor
Universal Diagnostics
NCT number
NCT07310446

What you commit to

  • Study type: Observational
  • Planned participants: 6500
  • From 31 Jul 2023 to the primary completion date, 31 Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Arm B: Past history of CRC

Other

  • Arm A: Undergoing treatment for CRC,

Who the study is looking for

  • Arm A: Diagnosed with CRC
  • Arm B: Undergoing screening with colonoscopy for CRC

Age in the registry: 45 years to 84 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Gastroenterology and Internal Medicine Specialists
Coordinator of this site? Confirm its status
Lake BarringtonUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.