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NCT07311954Not yet recruiting

Development and Validation of a cCTA and Biomarker Based Risk Model for Coronary Revascularization in Elderly Patients With Coronary Artery Disease

Source: ClinicalTrials.gov · Last updated 31 Dec 2025

Brief summary (registry, in English)

This study is a prospective multi-center observational cohort involving elderly patients (≥70 years old) with multi-vessel coronary disease identified by coronary computed tomography angiography (cCTA) and scheduled for invasive coronary angiography. Data collection about cCTA, frailty and biomarkers and two-year follow-up will be conducted to develop and validate a risk model of coronary revascularization.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
800 (estimated)
First submitted
17 Dec 2025
Start date
1 Jan 2026
Primary completion date
1 Jan 2029
Lead sponsor
China National Center for Cardiovascular Diseases
NCT number
NCT07311954

What you commit to

  • Study type: Observational
  • Planned participants: 800
  • From 1 Jan 2026 to the primary completion date, 1 Jan 2029
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Previous coronary revascularization, including percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG).

Other illness

  • Acute myocardial infarction at admission, according to electrocardiographic findings and elevated cardiac biomarkers consistent with acute MI.

Other

  • Poor-quality CCTA images that prevent accurate assessment of coronary plaque characteristics or stenosis severity.
  • Refusal or inability to participate in the study or to provide informed consent.

Who the study is looking for

  • Age ≥ 70 years.
  • Multivessel coronary artery disease identified on coronary computed tomography angiography (CCTA), defined as ≥50% stenosis in at least two of the three major epicardial coronary arteries.
  • Scheduled to undergo invasive coronary angiography as part of standard clinical care.
  • Able to provide informed consent, or consent provided by a legally authorized representative.

Age in the registry: 70 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.